PMID: 9421119Jan 8, 1998Paper

Seroprevalence of Helicobacter pylori in German infants and children

Helicobacter
F HornemannP Bartmann

Abstract

The purpose of the study was to evaluate the serological prevalence of Helicobacter pylori (H. pylori) infection during infancy and childhood in Germany. We quantified specific IgG antibody titers against H. pylori by enzyme-linked immunosorbent assay (ELISA) technique (BIO-RAD G.A.P. IgG-test) from healthy children under 18 years (n = 216) admitted to hospital for minor surgical procedures. All patients were age 0-18 years and lived in the southern part of Germany (Bavaria and Baden-Wuerttemberg). For each age group, 12 different sera were obtained and were determined in duplicate. We analyzed the 216 sera within 6 age groups of equal size. Mean titers > 19 U/ml were considered positive for H. pylori infection. None of the sera of 48 children less than 4 years old were positive for anti-H. pylori specific IgG antibodies. Titers above 19 U/ml were found in 8.3% (3/36 sera each, CI 95% 1-21.7%) in the children age three to five and nine to 11 years. Six- to eight-year-old children showed a 19.4% seroprevalence (7/36 sera, CI 95% 8.2-48%) and children 12-14 years old showed a seropositivity of 16.7% (6/36 sera, CI 95% 6.6-46.1%). In contrast, 47.2% (17/36 sera, CI 26.5-70.3%) of the adolescents older than 14 years had positive H....Continue Reading

References

Apr 1, 1991·Journal of Clinical Pathology·J E CrabtreeJ I Wyatt
Aug 1, 1989·Journal of Clinical Microbiology·F MégraudD Q Hoa
Feb 1, 1989·Gastroenterology·D Y Graham
Jun 18, 1987·The New England Journal of Medicine·B DrummM Karmali
Jan 1, 1993·Transactions of the Royal Society of Tropical Medicine and Hygiene·C HolcombeD M Jones
Apr 1, 1993·Journal of Pediatric Gastroenterology and Nutrition·U BleckerY Vandenplas
Mar 1, 1996·Archives of Disease in Childhood. Fetal and Neonatal Edition·M AshornM Mäki
Jan 1, 1996·European Journal of Gastroenterology & Hepatology·T BreuerP Malfertheiner
Dec 24, 1997·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·C S Goodwin

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Citations

Feb 17, 2001·Archives of Medical Research·J TorresO Muñoz
Oct 21, 2011·Clinical and Vaccine Immunology : CVI·Thomas WexPeter Malfertheiner
May 2, 2014·Gut Pathogens·Angelika MichelTim Waterboer
Apr 17, 2002·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Miyazaki MiyazakiHiroshi Une
Apr 22, 2006·Diagnostic Microbiology and Infectious Disease·Kaija-Leena KolhoHilpi Rautelin
Aug 13, 1999·The American Journal of Gastroenterology·T FujisawaY Matsunaga
Apr 8, 2004·Helicobacter·M Constanza CamargoCorrea Pelayo

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