Seroprevalence of hepatitis and HIV infection among rural pregnant women in Cameroon

APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica
P M NdumbeH I Joller-Jemelka

Abstract

Since some hepatitis viruses and the human immunodeficiency viruses share common modes of transmission, such as the sexual route, we undertook to investigate the prevalence of antibodies to these and other pathogens among 384 rural pregnant women. Our study was intended to form the basis of infection management policies in pregnancy. Antibodies and other markers of the hepatitis A, B, C, and D viruses (HAV, HBV, HCV, HDV), the human immunodeficiency virus type 1 (HIV-1) and Treponema pallidum were sought. We tested for antibodies to the viruses using the appropriate enzyme-linked immunosorbent assays. HCV and HIV-1 infection were confirmed using standard immunoblotting techniques. Regarding HBV, we tested for the surface antigen (HBsAg), antibody to the surface antigen (anti-HBs) and antibody to the core antigen (anti-HBc). A non-specific test, the rapid plasma reagin test (RPR), was used for estimating Treponema pallidum (syphilis) infection. We found an overall prevalence of antibodies to HAV of 91.4%, to HCV of 6.8%, to HDV of 0%, and to HIV-1 of 3.5%. We found no IgM antibodies to HAV. The incidence of HBV markers was as follows: 5.4% for HBsAg, 61.3% for anti-HBs, and 84.6% for anti-HBc. RPR reactivity was found in 15.8% o...Continue Reading

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Citations

Oct 23, 1998·Research in Virology·S AghaM Fawzy
Jan 8, 2004·AIDS Research and Human Retroviruses·David Gisselquist
Jan 15, 2003·Journal of Medical Virology·Richard NjouomEric Nerrienet
Sep 21, 2005·Journal of Medical Virology·Christophe PasquierEric Nerrienet
Jan 19, 1999·The Journal of Infection·S D AhmedC A Hart
Sep 6, 2005·Médecine et maladies infectieuses·D ReyJ M Lang
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Sep 1, 2016·Infectious Diseases in Obstetrics and Gynecology·Jodie Dionne-OdomAlan T N Tita
Oct 1, 2015·Iranian Red Crescent Medical Journal·Hasan AfzaliMaryam Poorrahnama

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