PMID: 15361991Sep 14, 2004Paper

Seroprevalence of hepatitis B and C in the Western Brazilian Amazon region (Rio Branco, Acre): a pilot study carried out during a hepatitis B vaccination program

The Brazilian Journal of Infectious Diseases : an Official Publication of the Brazilian Society of Infectious Diseases
José Tavares-NetoRaymundo Paraná

Abstract

In 1999, on the occasion of the application of the first vaccine dose during the state vaccination campaign against hepatitis B virus (HBV), 390 individuals from the town of Rio Branco, Acre, aged two or more years were selected for the determination of the seroprevalence of HBV and HCV. HBV markers (HBsAg, anti-HBs, and anti-HBc IgG) were determined on this occasion and anti-HBs antibodies were also assessed 30 days after the third vaccine dose. At the time of vaccination, 39% of the individuals were still susceptible to HBV, while 61% presented serologic evidence of previous HBV contact or previous vaccination. The individuals with previous HBV contact were significantly older (p<0.001) than those without HBV markers. Of the 192 individuals who returned for reexamination, 30 days after the third dose, 158 (82.3%) had received three vaccine doses, and only 60 (31.2%) belonged to the group without HBV markers. In these individuals, the seroconversion rate after the third dose was 92% (55/60). In conclusion, we found considerable HBV in this population, indicating the need for pursuing the immunization programs. We also found high rates of vaccination coverage in the Western Brazilian Amazon region.

Citations

Oct 20, 2012·Journal of Medical Virology·Marcella Kelly Costa de AlmeidaLuisa Caricio Martins
Dec 23, 2015·Revista Da Sociedade Brasileira De Medicina Tropical·Francisco José Dutra Souto
Dec 23, 2009·Memórias do Instituto Oswaldo Cruz·Alexandre Martins Portelinha FilhoLuiz Euribel Prestes-Carneiro
Aug 22, 2012·The American Journal of Tropical Medicine and Hygiene·Márcia da Costa CastilhoWornei Silva Miranda Braga
Oct 2, 2014·Revista brasileira de epidemiologia = Brazilian journal of epidemiology·Maria Célia Cunha CiacciaGilda Porta
Oct 15, 2008·Revista Da Sociedade Brasileira De Medicina Tropical·José Américo AquinoLuiz Fernando Almeida Machado
Mar 9, 2010·Memórias do Instituto Oswaldo Cruz·Aldemir B Oliveira-FilhoJosé Alexandre R Lemos
Apr 23, 2020·Scientific Reports·Livia Alves LimaAna Rita Coimbra Motta-Castro
Feb 22, 2014·BMC Infectious Diseases·Myuki Alfaia Esashika CrispimDagmar Kiesslich
Oct 15, 2010·Memórias do Instituto Oswaldo Cruz·Adriana Cristina da SilvaMaria Cássia Jacintho Mendes-Correa
Jul 29, 2006·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Wanessa Teixeira Bellíssimo-RodriguesJosé Fernando C Figueiredo

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