Seroprevalence of IgG antibodies against measles in a selected Polish population - do we need to be re-vaccinated?

Central-European Journal of Immunology
Justyna HolkaOlga Ciepiela

Abstract

Measles is highly contagious, but preventable viral disease. Its outbreaks appear all over the world, and decreasing herd immunity excludes its elimination. High levels of IgG antibodies against a virus efficiently protects against infection. To assess the seroprevalence of anti-measles IgG in the serum of patients at different age levels tested for measles IgG at our laboratory. The study was conducted from March to June of 2019. Retrospective analysis included results for measles-specific IgG from 364 tested patients. The age of enrolled subjects ranged from four months to 101 years, with a median age of 46, and a mean age of 43 ±18. Quantification of anti-measles IgG was performed using indirect chemiluminescence immunoassays on the DiaSorin Liaison® automated analyzer. Our results showed a seropositivity ratio of 78.02%. The lowest number of seropositive subjects was in the group of infants (0-1 years old), with a ratio of 53.85%, and the group of adults of 19-38 years old at 55.68%. The group of the oldest patients (70-101 years old) had the highest ratio of seropositive subjects (100%), while adults of 60-69 years old had a seropositivity ratio of 97.22%. These data suggest that the group of young adults who were vaccinat...Continue Reading

Citations

Oct 6, 2020·Human Vaccines & Immunotherapeutics·Luca CoppetaAndrea Magrini
Jul 1, 2021·Advanced Science·Caitlin D BohannonSuryaprakash Sambhara

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