Seroprevalence of Measles, Mumps, and Rubella Antibodies in College Students in Mumbai, India

Viral Immunology
Devanshi J GohilAbhay S Chowdhary

Abstract

Measles, Mumps, and Rubella (MMR) are vaccine preventable viral infections, which cause significant mortality and morbidity globally. Increased incidence rates of these infectious diseases are observed in young adults. Information on seroprevalence data on MMR in India is limited. The objective of this study was to determine the prevalence of IgG antibodies against MMR among young adults. This was a descriptive cross-sectional study involving 192 healthy college students from Maharshi Dayanand College, Mumbai. The project was approved by the Institutional Ethics Committee of Haffkine Institute. Between December 2012 and September 2013, blood samples were collected from individuals of age 18-23 years after obtaining written informed consent from them. The quantitative determination of IgG antibodies in serum specimens against MMR was determined using enzyme linked immunosorbent assay. Data on history of vaccination were also collected from participants. Among 192 healthy college students (age 18-23 years), MMR seroprevalence was 91%, 97%, and 88%, respectively. The overall seropositivity of MMR was 79%. The highest level of seronegativity was seen with regards to rubella-specific antibodies in 12% of cases. About 96% of the part...Continue Reading

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Citations

Mar 18, 2017·Indian Journal of Medical Microbiology·Valsan Philip Verghese
Aug 23, 2016·Pharmacogenomics·Javier Ampuero, Manuel Romero-Gómez
Aug 11, 2016·International Journal of Adolescent Medicine and Health·Misaki KatsuyamaKazuhiro Kogawa
Mar 22, 2020·Scientific Reports·Cassia Fernanda EstofoleteMauricio Lacerda Nogueira

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Methods Mentioned

BETA
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