Abstract
AbstractRickettsial infections are recognized as important causes of fever throughout southeast Asia. Herein, we determined the seroprevalence to rickettsioses within rural and urban populations of northern Vietnam. Prevalence of individuals with evidence of prior rickettsial infections (IgG positive) was surprisingly low, with 9.14% (83/908) testing positive to the three major rickettsial serogroups thought to circulate in the region. Prevalence of typhus group rickettsiae (TG)-specific antibodies (6.5%, 58/908) was significantly greater than scrub typhus group orientiae (STG)- or spotted fever group rickettsiae (SFG)-specific antibodies (P < 0.05). The majority of TG seropositives were observed among urban rather than rural residents (P < 0.05). In contrast, overall antibody prevalence to STG and SFG were both very low (1.1%, 10/908 for STG; 1.7%, 15/908 for SFG), with no significant differences between rural and urban residents. These results provide data on baseline population characteristics that may help inform development of Rickettsia serological testing criteria in future clinical studies.
References
Jan 1, 1990·Annual Review of Entomology·A F Azad
Aug 1, 1994·The American Journal of Tropical Medicine and Hygiene·D StrickmanD J Kelly
Jul 1, 1997·The American Journal of Tropical Medicine and Hygiene·A L RichardsA L Corwin
Jan 5, 2002·International Journal of Systematic and Evolutionary Microbiology·J S DumlerF R Rurangirwa
Oct 28, 2003·Scandinavian Journal of Public Health. Supplement·Nguyen Thi Kim Chuc, Vinod Diwan
Jan 4, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Paul C F GrafAllen L Richards
Dec 15, 2010·PLoS Neglected Tropical Diseases·Julie ValléePaul N Newton
Jan 19, 2011·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Veasna DuongPhilippe Buchy
Nov 10, 2011·FEMS Immunology and Medical Microbiology·Allen L Richards
Sep 13, 2012·PloS One·Nathalie AcestorDavid Bell
Mar 29, 2014·PloS One·Trinh Tuyet DaoHeiman F L Wertheim
Jun 25, 2014·The American Journal of Tropical Medicine and Hygiene·Ar Kar AungStephen Graves
Aug 6, 2014·The American Journal of Tropical Medicine and Hygiene·Rapeephan R MaudeNicholas P J Day
Jan 27, 2015·The Lancet Global Health·Sabine DittrichPaul N Newton
Mar 18, 2015·The American Journal of Tropical Medicine and Hygiene·Sugihiro HamaguchiPham Thanh Thuy
Mar 27, 2015·Emerging Infectious Diseases·Jacqueline W ThigaJohn N Waitumbi
May 20, 2015·Vector Borne and Zoonotic Diseases·Stuart D BlacksellAllen L Richards
May 30, 2015·PloS One·Cherry LimDirek Limmathurotsakul
Citations
Nov 4, 2017·PLoS Neglected Tropical Diseases·Guang XuChristine M Arcari
Mar 19, 2019·Emerging Infectious Diseases·Nguyen Vu TrungNguyen Van Kinh
Aug 31, 2019·PloS One·Nguyen Vu TrungAllen L Richards
Aug 4, 2020·Vector Borne and Zoonotic Diseases·Sirirat PhomjareetAllen L Richards
Oct 8, 2019·Epidemiology and Infection·Matthew T RobinsonStuart D Blacksell
Apr 18, 2019·EcoHealth·Jaruwan SatjanadumrongStuart D Blacksell
Aug 6, 2020·Infection and Drug Resistance·Nam Le VanBinh Nhu Do
Mar 15, 2019·Emerging Microbes & Infections·Nhiem Le-VietPhilippe Parola
Apr 5, 2020·Tropical Medicine and Infectious Disease·Allen L Richards, Ju Jiang
Aug 25, 2020·3 Biotech·Deepak KalaAnkur Kaushal
Dec 15, 2020·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Philip N D EldersElizabeth A Ashley
Mar 7, 2021·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Jihye UmJun-Sun Park
Mar 20, 2021·Frontiers in Medicine·Ju JiangAllen L Richards
May 22, 2021·Asia-Pacific Journal of Public Health·Siraj A KhanR Sabarinanthan
Aug 26, 2021·PLoS Neglected Tropical Diseases·Tamalee RobertsPaul N Newton