PMID: 7781738Jun 1, 1995Paper

Serosurvey and laboratory diagnosis of imported sandfly fever virus, serotype Toscana, infection in Germany

Epidemiology and Infection
T F SchwarzC Pauli

Abstract

Of eight acute infections in German tourists caused by sandfly fever virus, serotype Toscana (TOS), and diagnosed clinically and serologically, seven were acquired during visits to Tuscany, Italy, and one to Coimbra, Portugal. An indirect immunofluorescence assay (IFA) using infected cells, and a newly developed enzyme-immunoassay (EIA) using crude virus antigen prepared from infected Vero-E6 cells was used to detect anti-TOS IgM and IgG. In a seroepidemiological survey of 859 health care workers and medical students, anti-TOS IgG was detected in 1.0% by IFA, and in 0.7% by EIA. In 2034 German patients hospitalized for various diseases, 1.6% were positive for anti-TOS IgG by IFA, and 0.8% by EIA. Anti-TOS IgG was detected in 43 samples of commercial immunoglobulins at titres of 10-1000 by EIA. Although the seroprevalence of antibodies to TOS is low in Germany, TOS infection should be considered in patients returning from endemic areas who complain of fever, and headaches, and have symptoms of meningitis.

References

May 1, 1976·The American Journal of Tropical Medicine and Hygiene·P J Bartelloni, R B Tesh
Jan 1, 1977·The American Journal of Tropical Medicine and Hygiene·R B Tesh, G Papaevangelou
Jan 1, 1991·Scandinavian Journal of Infectious Diseases·R EitremO Weiland
Sep 1, 1991·Research in Virology·R EitremB Niklasson
Jan 1, 1990·Archives of Virology·A G Bukrinskaya, N K Sharova
Jan 1, 1990·Archives of Virology·P Payment, E Morin
Aug 1, 1990·The American Journal of Tropical Medicine and Hygiene·R EitremB Niklasson
Jan 1, 1988·Annual Review of Entomology·R B Tesh
Jun 1, 1988·Journal of Virological Methods·T F SchwarzF Deinhardt
Dec 1, 1988·The American Journal of Tropical Medicine and Hygiene·D WattsK T McKee
May 25, 1985·Lancet·B Niklasson, R Eitrem
Jul 1, 1987·The American Journal of Tropical Medicine and Hygiene·F M FeinsodM Darwish
Jan 1, 1987·Transactions of the Royal Society of Tropical Medicine and Hygiene·M DarwishS el Said
Dec 1, 1994·Journal of Medical Virology·T F SchwarzG Jäger
Jun 25, 1994·Lancet·Y TselentisB Chaniotis
Sep 25, 1993·Lancet·T F SchwarzG Jäger
Mar 1, 1993·Transactions of the Royal Society of Tropical Medicine and Hygiene·A CorwinM Kilpatrick

Citations

Jan 29, 1999·Research in Virology·T F SchwarzH M Schätzl
Mar 15, 2011·Vector Borne and Zoonotic Diseases·Koray ErgünayMatthias Niedrig
Jun 3, 2010·The Open Virology Journal·Maria Grazia CusiGiacomo Zanelli
Dec 2, 2005·Emerging Infectious Diseases·Rémi N. CharrelXavier de Lamballerie
Jun 23, 2007·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Mercedes Pérez-RuizAntonio Tenorio
Apr 7, 2004·Medicina clínica·José María NavarroMaría-Paz Sánchez-Seco
Feb 2, 2012·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Selma GulerYavuz Uyar
Mar 22, 2008·Virology·Gianni Gori SavelliniMaria Grazia Cusi
Feb 15, 2005·Virology·Maria Grazia CusiClelia Miracco
Apr 20, 2012·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·V Punda-PolićK Šiško Kraljević
Jun 1, 1996·Journal of Medical Virology·T F SchwarzG Jäger
Apr 3, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Daniele DionisioC Lupi
Nov 1, 2013·World Journal of Virology·Rémi N. CharrelXavier de Lamballerie
Oct 12, 2002·Journal of Medical Virology·Paola Di BonitoColomba Giorgi
Jul 15, 2003·Journal of Medical Virology·María-Paz Sánchez-SecoAntonio Tenorio
Aug 4, 2011·Expert Review of Anti-infective Therapy·Maria Grazia Cusi, Gianni Gori Savellini
May 10, 2003·Clinical and Diagnostic Laboratory Immunology·Marcello ValassinaMaria Grazia Cusi
Dec 4, 2010·The International Journal of Neuroscience·Daniele SerataRoberto Tatarelli
Nov 1, 2005·Journal of Travel Medicine·Gilles DefuentesThierry Debord
Dec 2, 2005·Emerging Infectious Diseases·Sara Sanbonmatsu-GámezAntonio Tenorio
Sep 23, 2003·Current Opinion in Infectious Diseases·Daniele DionisioMarcello Valassina

Related Concepts

Antibodies, Viral
Polyglobin
IgM2
Peroxidase-Antiperoxidase Complex Technique
Phlebotomus Fever
Serologic Tests
Travel
Time-Resolved Immunofluorometric Assay
Seroprevalence
Sandfly Fever Sicilian Virus

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