PMID: 11918524Mar 29, 2002Paper

Serotonergic agents in the treatment of fibromyalgia syndrome

The Annals of Pharmacotherapy
Lisa J Miller, Kristy L Kubes

Abstract

To evaluate literature that discusses the treatment of fibromyalgia syndrome (FMS) with agents that involve the neurotransmitter serotonin. Biomedical literature accessed through MEDLINE (1966-August 2001) and International Pharmaceutical Abstracts. The cause and pathophysiology of FMS remain elusive, although abnormalities in the serotonin pathway have been implicated. Several serotonergic agents have been studied for use in FMS. Trials and case reports focusing on the use of newer agents: the selective serotonin reuptake inhibitors, venlafaxine and tramadol, were reviewed. Current research suggests that the serotonergic agents may reduce at least some of the symptoms of FMS. However, medications that act on multiple neurotransmitters may prove to be more effective in symptom management. Additional long-term studies are required in order to validate these results.

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Citations

Sep 7, 2013·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·F MateosJ González Macías
May 22, 2013·International Journal of Hepatology·Paulette Bioulac-SageCharles Balabaud
Jun 23, 2006·Arthritis Research & Therapy·Laura BazzichiStefano Bombardieri
Apr 29, 2010·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Huijuan CaoGeorge T Lewith
Feb 25, 2003·Current Opinion in Rheumatology·Haiko Sprott
Nov 2, 2004·Scandinavian Journal of Rheumatology. Supplement·J TolkW Müller
Jul 2, 2011·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Laura M TraynorAndrew P Traynor
Oct 13, 2005·The Annals of Pharmacotherapy·Patrick B WoodGloria S Caldito
Oct 22, 2002·Expert Opinion on Investigational Drugs·Kim Lawson
Oct 21, 2003·The Annals of Pharmacotherapy·Kemal SayarMehmet Tosun
Apr 20, 2012·The Cochrane Database of Systematic Reviews·Sera TortBrian Walitt
May 16, 2018·Frontiers in Medicine·Silvia Maria Lattanzio, Francesca Imbesi

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