Serotonin-immunoreactive CPT interneurons in Hermissenda: identification of sensory input and motor projections

Journal of Neurophysiology
Lian-Ming TianTerry Crow

Abstract

Serotonin immunoreactive (5-HT-IR) neurons identified as cerebropleural ganglion triplets (CPTs) in Hermissenda may be homologues of 5-HT-IR neurons identified in other opisthobranch molluscs. In studies of isolated nervous systems and semi-intact preparations we used a combination of immunohistochemical techniques and fluorescent labeling with Lucifer yellow to identify 5-HT-IR CPT neurons after investigating sensory inputs and motor neuron projections. Here we show that identified 5-HT-IR CPT interneurons receive sensory input from mechanoreceptors and photoreceptors. In semi-intact preparations with intact pedal nerves P1 and P2, cutaneous stimulation of the middle or tail regions of the foot with calibrated von Frey hairs elicited spikes recorded from identified CPT interneurons. Illumination of the eyes evoked a small complex excitatory postsynaptic potential (EPSP) and resulted in a modest increase in the spike discharge of CPT interneurons. Immunostaining of Lucifer yellow-labeled neurons revealed that CPT interneurons projected an axonal process to the contralateral pedal ganglion. Depolarization of CPT interneurons with extrinsic current evoked EPSPs and spikes recorded from identified VP2 pedal neurons, motor neurons ...Continue Reading

References

Jan 1, 1979·Comparative Biochemistry and Physiology. C: Comparative Pharmacology·G AudesirkA O Willows
Jan 1, 1992·Journal of Neurophysiology·D R McPherson, J E Blankenship
Oct 1, 1991·Journal of Neurophysiology·D R McPherson, J E Blankenship
Nov 1, 1989·Journal of Neurophysiology·D W Parsons, H M Pinsker
Jul 1, 1986·Journal of Neurobiology·R D Longley, A J Longley
Dec 1, 1972·The Journal of General Physiology·D L Akon, M G Fuortes
Aug 1, 1982·Behavioral and Neural Biology·R A PalovcikJ L Ram
May 1, 1995·Journal of Neurophysiology·Y V PanchinY I Arshavsky
Feb 1, 1994·Journal of Comparative Physiology. A, Sensory, Neural, and Behavioral Physiology·A D McClellanP A Getting
May 1, 1996·Experimental Brain Research·Y V PanchinA I Selverston
Feb 1, 1996·Trends in Neurosciences·P S Katz, W N Frost
Jan 1, 1995·Invertebrate Neuroscience : in·W G WrightB Maynard
Oct 6, 1999·Current Opinion in Neurobiology·P S Katz, R M Harris-Warrick
May 13, 2003·Journal of Neurophysiology·Terry Crow, Lian-Ming Tian
Jan 1, 1959·The Journal of General Psychology·R S ALBERTM CHASE

❮ Previous
Next ❯

Citations

Dec 21, 2006·Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology·James M Newcomb, Paul S Katz
Jun 22, 2011·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Paul S Katz
Aug 28, 2009·Journal of Neurophysiology·Nan Ge JinTerry Crow
Nov 17, 2012·Journal of Neurophysiology·Terry CrowLian-Ming Tian
Dec 17, 2008·Journal of Neurophysiology·Terry Crow, Lian-Ming Tian
Jun 23, 2012·Proceedings of the National Academy of Sciences of the United States of America·James M NewcombPaul S Katz
Sep 26, 2006·The Journal of Comparative Neurology·James M NewcombPaul S Katz
Jul 28, 2016·Current Opinion in Neurobiology·Paul S Katz
Jan 1, 2009·Reviews in the Neurosciences·Jian JingKlaudiusz R Weiss

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.