Serotonin receptors: their key role in drugs to treat schizophrenia

Progress in Neuro-psychopharmacology & Biological Psychiatry
Herbert Y MeltzerJunji Ichikawa

Abstract

Serotonin (5-HT)-receptor-based mechanisms have been postulated to play a critical role in the action of the new generation of antipsychotic drugs (APDs) that are usually referred to as atypical APDs because of their ability to achieve an antipsychotic effect with lower rates of extrapyramidal side effects (EPS) compared to first-generation APDs such as haloperidol. Specifically, it has been proposed by Meltzer et al. [J. Pharmacol. Exp. Ther. 251 (1989) 238] that potent 5-HT2A receptor antagonism together with weak dopamine (DA) D2 receptor antagonism are the principal pharmacologic features that differentiate clozapine and other apparent atypical APDs from first-generation typical APD. This hypothesis is consistent with the atypical features of quetiapine, olanzapine, risperidone, and ziprasidone, which are the most common treatments for schizophrenia in the United States and many other countries, as well as a large number of compounds in various stages of development. Subsequent research showed that 5-HT1A agonism may be an important consequence of 5-HT2A antagonism and that substitution of 5-HT1A agonism for 5-HT2A antagonism may also produce an atypical APD drug when coupled with weak D2 antagonism. Aripiprazole, the most ...Continue Reading

References

Feb 1, 1978·The American Journal of Psychiatry·Arvid Carlsson
Jan 1, 1976·Schizophrenia Bulletin·H Y Meltzer, Stephen M Stahl
Jun 24, 1976·Nature·Philip SeemanK Wong
Nov 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·Philip SeemanK Wong
Nov 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·D R BurtS H Snyder
May 1, 1975·Pharmakopsychiatrie, Neuro-Psychopharmakologie·H R BürkiT G White
Jan 1, 1991·Journal of Neural Transmission. General Section·R C Arora, H Y Meltzer
Feb 22, 1991·Science·T Sawaguchi, P S Goldman-Rakic
Apr 25, 1990·European Journal of Pharmacology·C P VanderMaelen, J P Braselton
Sep 9, 1986·European Journal of Pharmacology·J S Sprouse, G K Aghajanian
Jun 1, 1988·The Journal of Pharmacy and Pharmacology·J K ChiversC D Marsden
Aug 17, 1995·Nature·G V Williams, P S Goldman-Rakic
Oct 1, 1993·The British Journal of Psychiatry : the Journal of Mental Science·S J DuinkerkeH L Busard
Jul 1, 1994·Trends in Pharmacological Sciences·Philip Seeman, H H Van Tol
Jan 1, 1994·Acta Psychiatrica Scandinavica. Supplementum·Y D Lapierre
Apr 1, 1994·Brain Research. Molecular Brain Research·M PompeianoGuadalupe Mengod
Sep 15, 1993·Proceedings of the National Academy of Sciences of the United States of America·M RuatJ C Schwartz
Jun 20, 1996·European Journal of Pharmacology·P Salmi, S Ahlenius
Nov 1, 1996·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·P W BurnetP J Harrison
Nov 1, 1996·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Marie-Louise G WadenbergS Ahlenius
Nov 22, 1997·European Journal of Pharmacology·Marie-Bernadette AssiéWouter Koek
Jan 22, 1998·Proceedings of the National Academy of Sciences of the United States of America·R L Jakab, P S Goldman-Rakic
Feb 10, 1998·European Journal of Pharmacology·H RollemaS H Zorn
Jul 21, 1998·Journal of Affective Disorders·M A FryeR M Post
Jun 18, 1998·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·M MasellisJ L Kennedy
Oct 6, 1998·European Journal of Pharmacology·Adrian Newman-TancrediMark J Millan
Jan 12, 1999·British Journal of Pharmacology·A BoursonA J Sleight
Jan 14, 1999·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·W M Abi-SaabA Y Deutch
Feb 3, 1999·Annals of the New York Academy of Sciences·A J SleightA Bourson
Apr 3, 1999·British Journal of Pharmacology·Charlie ReavillT P Blackburn
Apr 30, 1999·The Journal of Clinical Psychiatry·R B Ostroff, J C Nelson
May 18, 1999·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·C P LawlerR B Mailman
Jul 31, 1999·Schizophrenia Research·J A Frederick, J H Meador-Woodruff
Aug 26, 1999·Neuropharmacology·N M Barnes, Trevor Sharp
Oct 12, 1999·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·J S SprouseS H Zorn
Feb 9, 2000·Trends in Pharmacological Sciences·P VanhoenackerJ E Leysen
Feb 10, 2000·Journal of Psychopharmacology·Marc Laruelle, Anissa Abi-Dargham
Feb 24, 2000·Naunyn-Schmiedeberg's Archives of Pharmacology·H L RowleyD J Heal
Jun 3, 2000·Annual Review of Pharmacology and Toxicology·T A Branchek, T P Blackburn
Jul 13, 2000·Neuroscience Letters·N L Zhukovskaya, John F Neumaier
Aug 6, 2000·Psychopharmacology·M Talvik-LotfiL Farde
Sep 7, 2000·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·K AntoniouZ Papadopoulou-Daifoti
Oct 24, 2000·Schizophrenia Research·S R McGurk, H Y Meltzer
Nov 4, 2000·The British Journal of Psychiatry : the Journal of Mental Science·C M StephensonLyn S Pilowsky
Jan 4, 2001·The American Journal of Psychiatry·Richard C SheltonH Y Meltzer
Feb 7, 2001·The American Journal of Psychiatry·P D Harvey, R S Keefe
Mar 30, 2001·Journal of Psychopharmacology·R A BantickPaul M Grasby
May 10, 2001·Biological Psychiatry·Tomiki SumiyoshiH Y Meltzer
Jun 8, 2001·Proceedings of the National Academy of Sciences of the United States of America·M F EganD R Weinberger
Oct 2, 2001·The American Journal of Psychiatry·T SumiyoshiH Y Meltzer
Oct 30, 2001·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·L A DawsonP Li
Nov 10, 2001·Psychopharmacology·D C Rogers, J J Hagan
Feb 19, 2002·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Junji IchikawaHerbert Y Meltzer
Mar 5, 2002·The Journal of Clinical Psychiatry·Michael E Thase
Jun 14, 2002·European Journal of Pharmacology·Shaun JordanC Anthony Altar
Jun 18, 2002·The Journal of Pharmacology and Experimental Therapeutics·Kevin D BurrisPerry B Molinoff
Sep 5, 2002·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·M M MarcusT H Svensson
Sep 13, 2002·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Stefania BonaccorsoJunji Ichikawa
Oct 9, 2002·International Clinical Psychopharmacology·David J Nutt
Jan 7, 2003·Archives of General Psychiatry·Herbert Y MeltzerInternational Suicide Prevention Trial Study Group
Nov 1, 1998·Trends in Cognitive Sciences·A F Arnsten

Citations

Sep 2, 2006·Naunyn-Schmiedeberg's Archives of Pharmacology·Marie-Bernadette AssiéAdrian Newman-Tancredi
Sep 4, 2009·Naunyn-Schmiedeberg's Archives of Pharmacology·Benoit LabonteGabriella Gobbi
Sep 28, 2007·Psychopharmacology·René HurlemannAndreas Bauer
Nov 15, 2007·Psychopharmacology·Kristian S JensenBirte Y Glenthøj
Dec 22, 2007·Psychopharmacology·Florian SchlagenhaufAndreas Heinz
Jul 4, 2009·Psychopharmacology·Satoshi YamamuraMotohiro Okada
Jan 12, 2012·Psychopharmacology·Philippe CorbeilEmmanuelle Pourcher
Aug 21, 2012·Psychopharmacology·Masaaki OgasaJohn Guarino
Jul 5, 2005·European Archives of Psychiatry and Clinical Neuroscience·Hans-Jürgen Möller
Jul 17, 2007·European Archives of Psychiatry and Clinical Neuroscience·Michael RiedelHans-Jürgen Möller
Mar 27, 2012·European Child & Adolescent Psychiatry·Eiji Kirino
Oct 1, 2008·Indian Journal of Clinical Biochemistry : IJCB·N GaurS Mishra
Mar 24, 2009·Lancet·Herbert Y Meltzer
Apr 18, 2008·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Mei HuangHerbert Y Meltzer
Nov 13, 2009·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Herbert Y MeltzerJoseph H Friedman
Oct 1, 2011·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Boris B QuednowFranz X Vollenweider
Jun 14, 2012·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Alison A WilliamsAmelia L Gallitano
Jan 16, 2008·Proceedings of the National Academy of Sciences of the United States of America·Vera Bubeníková-ValesováKarel Vales
Jan 12, 2010·Human Reproduction Update·Marleen M H J van GelderNel Roeleveld
Jun 16, 2009·Schizophrenia Bulletin·Gholson J LyonDavid Sulzer
Jun 3, 2009·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Catalin V Buhusi, Warren H Meck
Sep 19, 2006·BMC Pharmacology·Alexandra HamacherMatthias U Kassack
Dec 2, 2009·BMC Pharmacology·Desheng Lu, Dennis A Carson
Jun 29, 2012·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·George B StefanoRichard M Kream
Apr 3, 2007·Journal of Molecular Neuroscience : MN·Andrew J ThompsonSarah C R Lummis
Apr 28, 2010·Journal of Psychiatry & Neuroscience : JPN·Ridha Joober, Patricia Boksa
Oct 24, 2009·Neuropsychiatric Disease and Treatment·Delia Bishara, David Taylor
Mar 25, 2008·Therapeutics and Clinical Risk Management·Richard C Shelton
Aug 30, 2011·The Australian and New Zealand Journal of Psychiatry·Esther BlessingChristos Pantelis
Dec 16, 2005·Pharmacogenomics·Simone GuptaRitushree Kukreti
Feb 25, 2014·International Journal of Molecular Sciences·Kai YangJohn F MacDonald
Jan 19, 2013·Pharmacogenomics·Adrián LlerenaHumberto Fariñas
Nov 16, 2013·CNS Spectrums·Lewis A OplerStephen M Stahl
Sep 3, 2013·Progress in Neuro-psychopharmacology & Biological Psychiatry·Jiamei LianChao Deng
Jan 31, 2013·Experimental Neurology·Nicolas MorinThérèse Di Paolo
Jun 4, 2014·Proceedings of the National Academy of Sciences of the United States of America·Natalia V MalkovaPaul H Patterson
Apr 26, 2013·Experimental Brain Research·Philippe De DeurwaerdèreSylvia Navailles
Sep 17, 2015·Schizophrenia Bulletin·Karin E Borgmann-WinterChang-Gyu Hahn
Nov 20, 2009·The International Journal of Neuroscience·Katrin M KirschbaumUlrich Schmitt
Dec 9, 2004·Expert Opinion on Therapeutic Targets·David J Sanger
Jul 14, 2012·Expert Opinion on Therapeutic Patents·Enza LacivitaMarcello Leopoldo
Sep 2, 2008·Expert Review of Neurotherapeutics·Monsheel SodhiJames Meador-Woodruff
Nov 1, 2008·Expert Review of Clinical Pharmacology·Donard S DwyerEric J Aamodt
Jul 15, 2015·Expert Opinion on Emerging Drugs·Jonathan Tomas Lockwood, G Remington
Jul 12, 2011·Expert Opinion on Investigational Drugs·B H EbdrupB Y Glenthøj
Apr 23, 2004·Expert Opinion on Investigational Drugs·Ann M Mortimer
Nov 6, 2012·Expert Opinion on Drug Discovery·Frank I Tarazi, Jo C Neill
Sep 4, 2008·Expert Opinion on Emerging Drugs·Ofer AgidG Remington
Jul 31, 2009·Expert Opinion on Pharmacotherapy·William V Bobo, Richard C Shelton
Apr 12, 2011·Expert Opinion on Drug Metabolism & Toxicology·Silvio Caccia
May 16, 2007·Expert Opinion on Investigational Drugs·Martyn Wood, Charlie Reavill
Jul 11, 2009·Expert Opinion on Investigational Drugs·Robin Emsley
Jul 13, 2006·Current Medical Research and Opinion·Stéphane PotvinAlain Gendron
Feb 10, 2007·Current Medical Research and Opinion·Jean-Pierre DoréeS Valérie Tourjman
Apr 25, 2007·The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry·Cornelius SchüleRainer Rupprecht
Jan 27, 2016·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Kristoffer SahlholmPeter Århem
Dec 25, 2015·Behavioural Brain Research·Viviane Muniz da Silva FragosoGabriel Melo de Oliveira
Oct 2, 2012·Pharmacology & Therapeutics·Francesc Artigas
Jun 5, 2012·Journal of Psychiatric Research·Anna SchuhmacherRainald Mössner
Apr 24, 2012·Gene·Henning SchneiderEric Hawley
Feb 4, 2012·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Edith J LiemburgAndré Aleman
May 31, 2011·Neuropharmacology·Annalisa TassonePaola Bonsi
Apr 8, 2011·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Iluminada CorripioEnric Alvarez
Aug 31, 2010·Psychiatry Research·Tomiki SumiyoshiMasayoshi Kurachi
Sep 14, 2010·Clinics in Laboratory Medicine·Peter P Zandi, Jennifer T Judy
Dec 1, 2015·Pharmacology & Therapeutics·Giuseppe Di Giovanni, Philippe De Deurwaerdère
May 13, 2010·Pharmacology, Biochemistry, and Behavior·Yukihiro OhnoSaki Shimizu
Apr 20, 2010·Progress in Neuro-psychopharmacology & Biological Psychiatry·Saki ShimizuYukihiro Ohno
Feb 18, 2010·The Psychiatric Clinics of North America·Peter P Zandi, Jennifer T Judy
Feb 16, 2010·Nuclear Medicine and Biology·Nabeel NabulsiYu-Shin Ding
Nov 3, 2009·Progress in Neuro-psychopharmacology & Biological Psychiatry·B CapuanoW W Blessing
Aug 6, 2009·Progress in Neurobiology·Francesca GallettiPaola Sarchielli
Jun 23, 2009·Neuropharmacology·Rebecca E NordquistWill Spooren
Mar 25, 2009·Pharmacology & Therapeutics·Sarah Grimwood, Paul R Hartig
Dec 24, 2008·Brain Research Bulletin·Luciano GonçalvesMartin Metzger
Jul 8, 2008·Neuropharmacology·Kelly A BergUmberto Spampinato
Aug 19, 2008·Behavioural Brain Research·Herbert Y Meltzer, Tomiki Sumiyoshi
Jul 16, 2008·Neuropharmacology·Caitlin A Jones, Andrew C McCreary
Feb 19, 2008·The Journal of Emergency Medicine·Laurence BorrasCédric Hermans
Feb 20, 2008·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·Dallas R DonohoeDonard S Dwyer
Dec 28, 2007·Bioorganic & Medicinal Chemistry Letters·James M GrahamSham S Nikam
Sep 22, 2007·Journal of the American Academy of Child and Adolescent Psychiatry·Alexandra L SpornNitin Gogtay
Apr 10, 2007·Neuroscience and Biobehavioral Reviews·Alfredo Meneses, Georgina Perez-Garcia
Jan 2, 2007·Neuropharmacology·Vera Bubeníková-ValesováJiri Horacek
Nov 23, 2006·The Psychiatric Clinics of North America·Kathleen L Benson
Sep 13, 2015·Pharmacology, Biochemistry, and Behavior·Ayaka TataraYukihiro Ohno
Jan 29, 2009·Synapse·Stéphane PotvinSerge Marchand
Oct 24, 2006·Journal of Neurochemistry·Cornelis J Van der SchyfM B H Youdim
Feb 10, 2009·Journal of Neurochemistry·Michael T Klein, Milt Teitler
May 29, 2009·The European Journal of Neuroscience·H-P Landolt, R Wehrle
Jan 15, 2008·Acta Psychiatrica Scandinavica·Richard C Shelton, George I Papakostas
May 24, 2008·The Journal of Pharmacy and Pharmacology·Daniela J ConradoTeresa Dalla Costa
Mar 19, 2016·Neuroscience and Biobehavioral Reviews·Laura SteenbergenLorenza S Colzato
Oct 9, 2012·Chemical Biology & Drug Design·Vani MunusamyLip Yong Chung
Sep 29, 2011·Pharmacotherapy·Stephanie V Phan, Tiffany-Jade M Kreys
Jun 6, 2013·World Psychiatry : Official Journal of the World Psychiatric Association (WPA)·Donald C Goff
Dec 18, 2014·Psychogeriatrics : the Official Journal of the Japanese Psychogeriatric Society·Eiji Kirino
Jun 19, 2010·CNS Neuroscience & Therapeutics·Giuseppe Di GiovanniVincenzo Di Matteo
Mar 26, 2016·Progress in Neurobiology·Philippe De Deurwaerdère, Giuseppe Di Giovanni
Feb 8, 2005·General Hospital Psychiatry·Harpreet S Duggal
Dec 22, 2004·Progress in Neuro-psychopharmacology & Biological Psychiatry·Iluminada CorripioEnric Alvarez
Jan 12, 2005·European Psychiatry : the Journal of the Association of European Psychiatrists·Anissa Abi-Dargham, Marc Laruelle
Dec 14, 2004·European Journal of Pharmacology·Taco R WerkmanWytse J Wadman
Oct 7, 2004·European Journal of Pharmacology·Vera BubeníkováCyril Höschl
Aug 4, 2004·Neuroscience and Biobehavioral Reviews·Albert Adell, Francesc Artigas
Nov 6, 2007·Biochemical Pharmacology·William E FantegrossiChad J Reissig
Oct 20, 2006·Pharmacology & Therapeutics·K D Alex, Elizabeth A Pehek
Sep 12, 2006·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·Dallas R DonohoeDonard S Dwyer
Nov 25, 2015·The Psychiatric Clinics of North America·Jayesh KamathAndrew Winokur
Nov 23, 2005·Progress in Neuro-psychopharmacology & Biological Psychiatry·Tsuyoshi ArakiKiyoto Kasai
Nov 10, 2005·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Rudi HwangJ L Kennedy
Sep 15, 2005·Neuroscience and Biobehavioral Reviews·Julie G Hensler
Aug 17, 2005·Physiology & Behavior·Walter H KayeShannan E Henry
Jul 12, 2005·Pharmacology & Therapeutics·Ellen S Mitchell, John F Neumaier
Jul 12, 2005·Progress in Neuro-psychopharmacology & Biological Psychiatry·Teresa M du BoisXu-Feng Huang
Jun 24, 2005·Pharmacology, Biochemistry, and Behavior·M M Doat-MeyerhoeferR A Rabin
Oct 22, 2013·Progress in Neuro-psychopharmacology & Biological Psychiatry·Jing QiaoMing Li
Apr 16, 2013·Progress in Neuro-psychopharmacology & Biological Psychiatry·Wenqiang LiLuxian Lv
Jul 26, 2013·Journal of Pharmacological Sciences·Kinzo MatsumotoJun-Ichiro Oka
Sep 13, 2005·European Journal of Pharmacology·Johanna E OlijslagersWytse J Wadman
Jan 26, 2011·Schizophrenia Research·Maria Rosaria A MuscatelloRocco A Zoccali
Apr 9, 2015·Journal of Pharmacological Sciences·Saki ShimizuYukihiro Ohno
Aug 22, 2008·Schizophrenia Research·Jiajun ShiChunyu Liu
May 17, 2008·Behavioural Brain Research·Sally Martin, Maarten van den Buuse
Feb 7, 2015·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Chris A OosterhofPierre Blier
Mar 3, 2015·Journal of Molecular Graphics & Modelling·Xinli DuanMing Lei
Apr 1, 2011·Clinical Psychopharmacology and Neuroscience : the Official Scientific Journal of the Korean College of Neuropsychopharmacology·Na-Ri Kang, Moon-Doo Kim
Aug 30, 2012·Neurochemistry International·Osamu IchikawaKazuto Yamazaki
Aug 3, 2013·Progress in Neuro-psychopharmacology & Biological Psychiatry·Darakhshan J Haleem
May 1, 2012·Progress in Neuro-psychopharmacology & Biological Psychiatry·Ayaka TataraYukihiro Ohno
Jul 11, 2013·Progress in Neuro-psychopharmacology & Biological Psychiatry·Saki ShimizuYukihiro Ohno
Aug 24, 2010·Neuroscience and Biobehavioral Reviews·Yan-Chun Li, Wen-Jun Gao
Aug 1, 2014·Behavioural Brain Research·Davide Amato
Apr 5, 2013·The International Journal of Neuropsychopharmacology·Taro KishiNakao Iwata
Jun 12, 2013·The International Journal of Neuropsychopharmacology·José L Moreno, Javier González-Maeso
Sep 9, 2006·The International Journal of Neuropsychopharmacology·Clement C ZaiJ L Kennedy
Sep 28, 2007·The International Journal of Neuropsychopharmacology·Adrian Newman-TancrediDidier Cussac
Nov 1, 2007·The International Journal of Neuropsychopharmacology·Bob OranjeBirte Y Glenthøj
Jan 7, 2011·The International Journal of Neuropsychopharmacology·H SilverOrly Weinreb
Aug 15, 2014·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Hirotake HidaYukihiro Noda
Apr 5, 2014·Thérapie·Marleen M H J van GelderNel Roeleveld
Dec 15, 2010·Thérapie·Leila ChebaneCentres Régionaux de Pharmacovigilance Français
Sep 6, 2008·Progress in Brain Research·Toshihide KurokiTatsuo Nakahara
Nov 14, 2013·ACS Chemical Neuroscience·Philip Seeman
Jul 5, 2016·Schizophrenia Research·Anand Gururajan, Daniel Thomas Malone
Sep 6, 2008·Progress in Brain Research·Neil M RichtandRobert K McNamara
Sep 30, 2016·Neuropharmacology·Claire N J MeunierPhilippe M Fossier
Nov 25, 2006·Schizophrenia Research·C T Toro, J F W Deakin
Dec 7, 2013·Revista brasileira de psiquiatria : orgão oficial da Associação Brasileira de Psiquiatria, Asociación Psiquiátrica de la América Latina·Pedro H GobiraFabrício A Moreira
Apr 11, 2007·Arquivos de neuro-psiquiatria·Vivian BertolaHomero Vallada
Mar 31, 2017·International Journal of Molecular Sciences·Matea Nikolac PerkovicNela Pivac
Apr 8, 2017·Psychopharmacology·Rainer KraehenmannFranz X Vollenweider
Dec 13, 2005·Nature Reviews. Drug Discovery·Will SpoorenHerbert Y Meltzer
Oct 3, 2009·Bioorganic & Medicinal Chemistry Letters·Laura CarroChristian F Masaguer
Oct 10, 2007·Harvard Review of Psychiatry·W Gordon Frankle
Feb 17, 2017·Frontiers in Synaptic Neuroscience·Claire N J MeunierPhilippe M Fossier
Sep 6, 2011·Journal of Psychopharmacology·Erik T te BeekJoop M A van Gerven
Aug 12, 2010·Journal of Psychopharmacology·Caroline BiojoneFabrício A Moreira
Mar 1, 2008·Journal of Psychopharmacology·M ShahidE H F Wong
Mar 1, 2008·Journal of Psychopharmacology·Stéphane PotvinEmmanuel Stip
Jan 30, 2007·Journal of Psychopharmacology·James M StoneLyn S Pilowsky
Aug 23, 2008·Journal of Psychopharmacology·Frank I TaraziM Shahid
Aug 12, 2004·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Robert M BilderAnthony A Grace
Jan 5, 2005·Molecular Psychiatry·T Kishi, J K Elmquist
May 4, 2016·Therapeutic Advances in Psychopharmacology·Dasiel O Borroto-EscuelaKjell Fuxe
Oct 4, 2006·Nature Reviews. Drug Discovery·Peter ImmingAchim Meyer
Aug 22, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Piotr StępnickiAgnieszka A Kaczor
Jan 14, 2005·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Brian HitsmanDonald Hedeker
Jun 6, 2007·Molecular Psychiatry·Maria J Arranz, Jose de Leon
Aug 11, 2007·International Clinical Psychopharmacology·A Carlo AltamuraHerbert Y Meltzer
Jul 26, 2005·Journal of Psychiatric Practice·Franca CentorrinoRoss J Baldessarini
Dec 7, 2007·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Niels H JensenBryan L Roth
Feb 22, 2008·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·David ErritzoeBirte Y Glenthoj
Apr 27, 2005·The International Journal of Eating Disorders·Walter H KayeShannan E Henry
Feb 14, 2009·Nature Reviews. Drug Discovery·Gerhard GründerArvid Carlsson
Feb 25, 2009·The Pharmacogenomics Journal·C C ZaiJ L Kennedy
Nov 4, 2009·The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology·Seon Min DongByong Sung Kwak
Oct 16, 2009·Psychiatric Genetics·Ismail Al-JanabiJose de Leon
Jul 7, 2005·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Elizabeth A PehekOmar S Mabrouk
May 6, 2004·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Carli MirjanaClaudia Balducci
Jan 26, 2007·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Neil M RichtandRobert K McNamara
Sep 30, 2005·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Mirjana CarliClaudia Balducci
May 19, 2005·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Zhu LiHerbert Y Meltzer
Aug 27, 2005·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Robert M KesslerHerbert Y Meltzer
Oct 21, 2005·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Laurent BardinAdrian Newman-Tancredi
Feb 15, 2007·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Kristian S JensenBirte Y Glenthøj
Dec 24, 2008·Expert Review of Neurotherapeutics·Elizabeth Scarr, Brian Dean
Oct 5, 2012·Molecular Pharmacology·Ishier RaoteMitradas M Panicker
Apr 21, 2010·The Journal of Pharmacology and Experimental Therapeutics·Tadashi IshibashiMitsutaka Nakamura
Jan 18, 2006·The Journal of Pharmacology and Experimental Therapeutics·Norton H NeffMaria Hadjiconstantinou
Dec 15, 2006·Molecular Pharmacology·Jean-Claude MartelAdrian Newman-Tancredi
Feb 7, 2008·The Journal of Pharmacology and Experimental Therapeutics·William J ThomsenDominic Behan
Sep 8, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Juhyeon KimSun-Joon Min
Dec 7, 2017·Journal of Clinical Psychopharmacology·Lindsay-Rose Dykema
Jan 4, 2020·Science Advances·Sanghwa JeongMarkita P Landry
Sep 18, 2008·Neuroreport·Maureen L PetrunichGeorge Battaglia
Apr 10, 2007·European Psychiatry : the Journal of the Association of European Psychiatrists·Luca PaniGiorgio Marchese
Jan 12, 2020·Birth Defects Research·Santiago CerrizuelaManuel J Aybar
Sep 29, 2006·Neurochemical Research·Iván Pérez-NeriCamilo Ríos
Dec 14, 2004·CNS Drug Reviews·Marilyn A DaviesBryan L Roth
Oct 12, 2004·CNS Spectrums·Herbert Y Meltzer
Aug 1, 2007·Personalized Medicine·Catarina Correia, Astrid M Vicente
Jul 30, 2015·Behavioural Pharmacology·Ming Li
May 10, 2017·Frontiers in Neurology·Sara GarofaloGraham K Murray
Aug 10, 2018·Journal of Molecular Neuroscience : MN·Yong Kee Choi, Frank I Tarazi
Oct 19, 2019·Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·V M Vostrikov
Aug 21, 2015·Behavioural Pharmacology·Lena Wischhof, Michael Koch
Jul 22, 2018·Journal of Clinical and Experimental Neuropsychology·Maverick Clissold, Simon F Crowe

Related Concepts

Brain
Intropin
Dose-Response Relationship, Drug
Drug Interactions
Receptors, Tryptamine
Schizophrenia
Serotonin Antagonists
Antipsychotic Effect
Dopamine Effect
Serotonin Agonists

Related Feeds

Antipsychotic Drugs

Antipsychotic drugs are a class of medication primarily used to manage psychosis (including delusions, hallucinations, paranoia or disordered thought), principally in schizophrenia and bipolar disorder. Discover the latest research on antipsychotic drugs here

Adrenergic Receptors: Trafficking

Adrenergic receptor trafficking is an active physiological process where adrenergic receptors are relocated from one region of the cell to another or from one type of cell to another. Discover the latest research on adrenergic receptor trafficking here.

Basal Ganglia

Basal Ganglia are a group of subcortical nuclei in the brain associated with control of voluntary motor movements, procedural and habit learning, emotion, and cognition. Here is the latest research.