PMID: 2116973Aug 1, 1990Paper

Serotype-specific outbreak of group B meningococcal disease in Iquique, Chile

Epidemiology and Infection
C CruzI Canepa

Abstract

From 1979 to August 1987, there have been 178 cases of meningococcal disease in Iquique, Chile, a city of about 140,000. The attack rate for the last 5 years has been in excess of 20/100,000 per year, more than 20 times greater than for the country overall. The mortality rate was 6%. The disease occurred in patients with ages from 4 months to 60 years, but 89% of cases were in patients less than 21 years. The largest number of cases were in the age group 5-9 years (n = 54), but the highest incidence occurred in children less than 1 year of age (72.8/100,000 per year). The male/female ratio was 1.2. Cases occurred all year round with little seasonal variation. Of the 178 cases, 173 were biologically confirmed. Serogroup analysis of strains from 135 patients revealed A = 1, B = 124, C = 10. Forty-four group B strains from 1985-7 were serotyped: 15:P1.3 = 36, 15:NT = 4, 4:P1.3 = 2, NT:NT = 2. Ten of 11 of the outbreak strains tested were sulfadiazine-resistant. This is the first recognized outbreak caused by a Gp B:15 strain in South America. It shares many of the characteristics of outbreaks caused by closely related strains in Europe, such as a predilection for older children and adolescents, sulfadiazine-resistance, and sustain...Continue Reading

References

Jul 1, 1985·Reviews of Infectious Diseases·C E FraschJ T Poolman
May 1, 1986·Applied and Environmental Microbiology·R K SelanderT S Whittam
Sep 6, 1986·Lancet·K A CartwrightN D Noah
Jul 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·D A CaugantR K Selander

❮ Previous
Next ❯

Citations

Feb 24, 2006·Epidemiology and Infection·K H Dyet, D R Martin
Sep 14, 2012·Journal of Clinical Microbiology·Chivonne MoodleyUNKNOWN Group for Enteric, Respiratory and Meningeal Disease Surveillance in South Africa
Jun 23, 2010·BMC Infectious Diseases·Vanessa N Racloz, Silva J D Luiz
May 4, 2002·Lancet·Luis JódarDan M Granoff
Jul 23, 1998·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·D A Caugant
Apr 15, 2011·The Lancet Infectious Diseases·François CaronMuhamed-Kheir Taha
May 20, 2015·EBioMedicine·Odile B HarrisonDominique A Caugant
Sep 1, 2009·Travel Medicine and Infectious Disease·Mohamed K M Khalil, Ray Borrow
Oct 5, 2010·Journal of Travel Medicine·Jaffar A Al-TawfiqZiad A Memish
May 30, 2009·Vaccine·Lee H HarrisonMary E Ramsay
Oct 2, 1998·Revista Do Instituto De Medicina Tropical De São Paulo·C T SacchiL W Mayer
Oct 2, 1998·Revista Do Instituto De Medicina Tropical De São Paulo·C T SacchiL W Mayer
Jul 1, 1995·Revista Do Instituto De Medicina Tropical De São Paulo·C T SacchiA Sperb
Apr 7, 2007·The Pediatric Infectious Disease Journal·Sharon WongDiana Martin
Jul 11, 2006·Expert Review of Vaccines·Judith E MuellerBradford D Gessner
Dec 23, 2006·Expert Review of Vaccines·Ray Borrow, Elizabeth Miller
May 19, 2001·Canadian Journal of Microbiology·F E Ashton, D A Caugant
Jan 22, 2015·Expert Review of Vaccines·Jane WhelanMirna Robert-Du Ry van Beest Holle
Jan 1, 1996·Scandinavian Journal of Infectious Diseases·B G Iversen, P Aavitsland
Dec 17, 1997·Journal of Clinical Microbiology·N B SaundersW D Zollinger

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.