Serotypes of Streptococcus pneumoniae isolated from blood and cerebrospinal fluid related to vaccine serotypes and to clinical characteristics

Scandinavian Journal of Infectious Diseases
Stefan BergHelle Bossen Konradsen

Abstract

Pneumococci isolated from blood and cerebrospinal fluid from 1998 to 2001 in 2 counties in south-west Sweden were serotyped with the capsular reaction test. Of the 836 strains, 353 (42%), 598 (72%) and 789 (94%) belonged to serotypes included in the 7- and 11-valent pneumococcal conjugate vaccines and in the 23-valent polysaccharide vaccine, respectively. The most common serotype was type 1 (119 isolates) followed in descending frequency by serotypes 7F, 9V, 14, 4 and 12F (90-49 isolates per serotype). The coverage rates of the 7- and 11-valent conjugate vaccines among 58 strains isolated from children and adolescents 0-19 y of age were 46% and 93%, respectively. A comparison of clinical characteristics of infections caused by different serotypes showed that types 1 and 7F were less commonly associated with severe underlying diseases, that patients infected with these serotypes were younger than the average and, thus, had a lower case-fatality rate.

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Citations

Aug 19, 2010·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Daniel M WeinbergerMarc Lipsitch
Sep 20, 2008·Journal of Microbiological Methods·Margit S KaltoftHelle Bossen Konradsen
Nov 21, 2015·Médecine et maladies infectieuses·I D BaM Ba
Jun 19, 2014·Acta Microbiologica Et Immunologica Hungarica·Lakshmana Gowda KrishnappaPradeep Chikkabidare Shashidhar
Aug 25, 2009·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Daniel J IsaacmanRalf R Reinert
Sep 12, 2013·Vaccine·Susanna EspositoNicola Principi
Nov 11, 2015·BMC Infectious Diseases·Margrét Johansson GudjónsdóttirBirger Trollfors
Mar 8, 2013·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·M InghammarA Egesten
Oct 18, 2014·The European Respiratory Journal·Sarah BrowallBirgitta Henriques-Normark
Mar 13, 2015·The Pediatric Infectious Disease Journal·Shalom Ben-ShimolIsraeli Bacteremia and Meningitis Active Surveillance Group
Mar 17, 2007·Scandinavian Journal of Infectious Diseases·Erik BackhausKerstin Andersson
Apr 28, 2011·Current Opinion in Infectious Diseases·Esther Calbo, Javier Garau
Nov 18, 2008·Scandinavian Journal of Infectious Diseases·Birger TrollforsHelle Bossen Konradsen

Related Concepts

Decline, Mortality
Pneumococcal Infections
Serotyping
Streptococcus pneumoniae
Vaccines, Conjugate
Streptococcal Vaccines

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