Serrated polyps: new classifications highlight clinical importance

Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland
C A MessickM F Kalady

Abstract

Many lesions previously classified as hyperplastic polyps and therefore thought to be innocuous have been reclassified as sessile serrated adenomas/polyps (SSA/Ps), establishing their place in the serrated pathway and underscoring their malignant potential. The clinical relevance of this new nomenclature is incompletely defined. This study examines the incidence and characteristics of colorectal SSA/Ps and describes other associated colorectal neoplasia. A single institution pathology database was searched for the diagnosis of SSA/Ps between January 2004 and October 2007. SSA/Ps found by colonoscopy were included. Patient demographics, SSA/P characteristics and associated colonoscopic findings were retrospectively recorded. A total of 585 SSA/Ps were removed during 519 colonoscopies in 483 patients performed by 64 different endoscopists. This represented an overall incidence of SSA/Ps per colonoscopy of 2.1% in the 28,054 colonoscopies performed during the study period. The median SSA/P size was 0.8 cm (range 0.2-4.5) and 188 (69%) were ≥ 1.0 cm. Of the 585 SSA/Ps, 366 (63%) were right-sided, 129 (22%) were in the left colon and 90 (15%) were in the rectum. Also, 439 synchronous polyps of other histology (mainly adenomas and hy...Continue Reading

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Citations

Oct 11, 2012·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·N Haboubi
Oct 9, 2013·Journal of Biomedical Science·Jing LiuZiqi Zhang
Mar 10, 2017·Scandinavian Journal of Gastroenterology·Henrik ThorlaciusErvin Toth
Jun 4, 2019·Journal of Gastroenterology and Hepatology·Takashi MurakamiAkihito Nagahara
Mar 23, 2020·Gastroenterology·Reinier G S MeesterUri Ladabaum

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