PMID: 18404970Apr 15, 2008Paper

Serum adiponectin, C-reactive protein and TNF-alpha levels in obese Korean children

Journal of Pediatric Endocrinology & Metabolism : JPEM
Jung Yeon ShinKee-Hyoung Lee

Abstract

To determine whether there are differences of serum adiponectin, CRP and TNF-a levels between obese and non-obese children and to investigate the relationship between childhood obesity and inflammation. A total of 103 (73 obese, 30 non-obese) children were evaluated for height, weight, blood pressure and body mass index (BMI). We measured serum adiponectin, hs-CRP, and TNF-alpha levels and analyzed their correlation with BMI, serum glucose, lipid profile and insulin resistance. Serum adiponectin levels were significantly decreased in the obese children compared to non-obese children, and had a negative correlation with BMI, fasting glucose and HOMA-IR. Serum hs-CRP and TNF-alpha levels were increased in obese children compared to non-obese children, and had a positive correlation with BMI. Serum adiponectin level was decreased and serum CRP and TNF-alpha levels were increased in obese children. Our findings suggest that childhood obesity is associated with inflammatory processes.

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Citations

Oct 23, 2010·Pediatric Pulmonology·Rakesh BhattacharjeeDavid Gozal
Sep 22, 2011·Journal of Pediatric Endocrinology & Metabolism : JPEM·Shali Mazaki-ToviEyal Sivan
Oct 11, 2014·Mind, Brain and Education : the Official Journal of the International Mind, Brain, and Education Society·Alison L MillerJulie C Lumeng
Nov 12, 2016·Endocrinology and Metabolism·Kyoung Hwa Ha, Dae Jung Kim
Jun 21, 2019·Molecular and Cellular Biochemistry·Limin TaoYanfeng Gong
Sep 19, 2009·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Yanhua PengMichel M Murr
Feb 12, 2009·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·F BoesingE A M Moreira
May 18, 2021·Frontiers in Immunology·Cesare TripolinoFrancesco Ursini

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