PMID: 6402995Mar 1, 1983Paper

Serum albumin levels in cancer patients receiving total parenteral nutrition

Annals of Surgery
R L McCauley, M F Brennan

Abstract

Serum albumin concentration is commonly used as an index of nutritional status and as an indicator of nutritional response in hospitalized patients receiving total parenteral nutrition (TPN). One hundred thirty-nine cancer patients receiving TPN for at least two weeks were studied. Albumin intake, serum albumin, fluid balance, and weight change was monitored from 14 to 100 days of TPN. Patients were classified into three groups: A) patients receiving no exogenous albumin; B) patients receiving less than 25 grams of exogenous albumin; and C) patients receiving at least 25 grams of exogenous albumin during their course of TPN. Linear regression analysis of serum albumin levels vs. time on TPN showed a minimal positive correlation for patients in groups B and C (r = 0.154 and r = 0.183, respectively). Further analysis showed a significant elevation of serum albumin levels only in patients in group C (p less than or equal to 0.05). Contingency table analysis showed statistically significant increase in the incidence of sepsis in patients treated with exogenous albumin (X2 = 10.50, df = 2, p less than 0.01). There was no relationship between the change in serum albumin concentrations and the number of patient deaths. In addition, no...Continue Reading

References

Mar 26, 1977·Lancet·G L HillD B Morgan
Jan 1, 1977·JPEN. Journal of Parenteral and Enteral Nutrition·G L BlackburnM F Smith
May 1, 1979·Cancer·E M CopelandS J Dudrick
Sep 1, 1979·Postgraduate Medical Journal·R V HeatleyM H Lewis
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Oct 26, 1972·The New England Journal of Medicine·F D Moore, M F Brennan
May 1, 1980·The American Journal of Medicine·D W NixonD Rudman
Jul 1, 1980·JPEN. Journal of Parenteral and Enteral Nutrition·G F ReinhardtR T Stannard
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May 1, 1980·JPEN. Journal of Parenteral and Enteral Nutrition·D M HickmanC F Frey

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Citations

Aug 1, 1992·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·F Bozzetti
Apr 1, 1994·The Annals of Pharmacotherapy·R G D'Angio
Jul 11, 1991·JPEN. Journal of Parenteral and Enteral Nutrition·D E CarlsonB A Pruitt
Jul 1, 1989·JPEN. Journal of Parenteral and Enteral Nutrition·F Bozzetti
Sep 1, 1987·JPEN. Journal of Parenteral and Enteral Nutrition·F Bozzetti
May 24, 2017·The Journal of Urology·Rohan G BhallaMark D Tyson
Jul 1, 1985·Journal of Surgical Oncology·D M OtaM Foulkes
Jul 1, 1986·Current Problems in Cancer·D M OtaK Diamond

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