PMID: 41902Nov 1, 1979

Serum and peritoneal fluid concentrations of clindamycin and lincomycin in the mouse

The Journal of Pharmacy and Pharmacology
A RosenL G Brookes


Serum concentrations of drug were obtained at various times after intramuscular dosing of healthy mice with either clindamycin or lincomycin hydrochlorides. Washings from the peritoneal cavity were taken at the same time as the serum samples. Changes in drug concentration in the peritoneal fluid with time mimic those for the serum, but concentrations in peritoneal fluid are much greater than the corresponding serum concentrations. The total volume of peritoneal fluid was estimated to be 0.05 ml.


Jan 1, 1983·Equine Veterinary Journal·S Dyson


Mar 1, 1977·The Journal of Infectious Diseases·T D WilkinsA A Salyers
Jul 1, 1972·The British Journal of Oral Surgery·A A Quayle, V B Whitmarsh
Apr 1, 1973·Journal of Pharmacokinetics and Biopharmaceutics·A A ForistC M Metzler
Jul 1, 1968·The American Journal of the Medical Sciences·J G WagnerW L Lummis
Jan 1, 1967·Clinical Pharmacology and Therapeutics·J G Wagner
Aug 1, 1957·Proceedings of the Society for Experimental Biology and Medicine·J MUNOZ

Related Concepts

Peritoneal Fluid (Body Substance)
Dalacin C
Lincomycin Monohydrochloride, (L-threo)-Isomer

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