Serum anti-Müllerian hormone in subfertile women

Acta Obstetricia Et Gynecologica Scandinavica
Edgardo SomiglianaLuigi Fedele

Abstract

The correlation between ovarian reserve and infertility remains unclear. Albeit poorly predictive of pregnancy success in in vitro fertilization cycles, serum anti-Müllerian hormone (AMH) has been acknowledged as a surrogate measure of ovarian reserve and is commonly evaluated in women seeking pregnancy. Disentangling whether low serum AMH affects natural fecundity is clinically important, as this information helps physicians in providing appropriate counseling to women and may impact on management strategies. This was a nested case-control study from a prospective cohort of pregnant women undergoing first trimester screening for aneuploidies. Cases were subfertile women having tried to become pregnant for 12-24 months. Controls were subsequent age-matched fertile women. Inclusion criteria for both cases and controls were: (i) age > 18 years, (ii) natural conception, (iii) regular menstrual cycles (24-35 days). We used quantitative detection of serum AMH and interviews with the women. The main outcome measure was the proportion of women with serum AMH < 1.1 ng/mL. Seventy-six subfertile women and 76 matched fertile controls were selected. In the two study groups, there were 11 (15%) and 15 (20%) women with serum AMH < 1.1 ng/mL...Continue Reading

References

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Citations

Apr 10, 2016·Human Reproduction·Edgardo SomiglianaPaolo Vercellini
Oct 17, 2018·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Iñaki González-ForuriaBuenaventura Coroleu
Oct 27, 2018·Journal of Assisted Reproduction and Genetics·Edgardo SomiglianaPaolo Vercellini
Mar 15, 2019·Current Opinion in Obstetrics & Gynecology·Baris AtaEmre Seli
Dec 6, 2017·Human Reproduction·Fedro Alessandro PeccatoriEdgardo Somigliana
Aug 19, 2018·Journal of Assisted Reproduction and Genetics·Andrea BusnelliEdgardo Somigliana
Jul 14, 2021·Human Reproduction Update·Andrea BusnelliPaolo Emanuele Levi-Setti
Jul 10, 2021·Fertility and Sterility·Francesca FilippiMonica Terenziani

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