PMID: 6168307Jul 1, 1981Paper

Serum beta-2-microglobulin in African Burkitt tumour, nasopharyngeal carcinoma and controls

Biomedicine / [publiée Pour L'A.A.I.C.I.G.]
E H CooperP Gunvèn

Abstract

Serum beta2-microglobulin measurements were made in Burkitt lymphoma and nasopharyngeal carcinoma in Africans and infectious mononucleosis in Europeans. There was a significant increase of beta2-microglobulin levels in active Burkitt tumour compared to those in remission but young West African children have higher levels than that in Caucasians. Nasopharyngeal carcinoma can be associated with a raised beta2-microglobulin but the distribution is similar to that seen in other head and neck cancers. In 27 cases of infectious mononucleosis 74% have raised levels of serum beta2-microglobulin. The mechanism of production of high serum beta2-microglobulin levels in rural African children is as yet unknown.

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