Serum biomarkers for thyroid cancer.

Biomarkers in Medicine
Qian XiaoZhaowei Meng

Abstract

The high prevalence of thyroid cancer requires a reliable serum biomarker for diagnosis and prognostic monitoring. Serum thyroglobulin has been established as the primary postoperative and postablative monitoring biomarker for this malignancy. However, the presence of thyroglobulin antibody imposes a significant interference on its overall management, which cannot be diminished by currently available assays. Trends on the level of the thyroglobulin antibody during follow-up is considered as a surrogate biomarker, but controversy exists. A variety of alternative biomarkers are being proposed and investigated, nevertheless, clinical trials and prospective validations are needed before they can be regarded as clinically viable serum parameters for thyroid cancer.

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Citations

Jun 9, 2021·Experimental and Molecular Pathology·Sen HouCheng-He Lin
Jun 11, 2021·Frontiers in Chemistry·Gurpal SinghRavi Pratap Barnwal

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Methods Mentioned

BETA
PCR

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