Serum bisphenol A and progression of type 2 diabetic nephropathy: a 6-year prospective study

Acta Diabetologica
Jinbo HuQifu Li

Abstract

Bisphenol A (BPA) is associated with diabetes and cardiovascular diseases. The aim of our study was to evaluate whether serum BPA could predict the progression of chronic kidney disease (CKD) in patients with type 2 diabetes (T2D). In this prospective study, a total of 121 patients with T2D and estimated glomerular filtration rate (eGFR) ≥ 60 mL/min/1.73 m(2) were followed up for 6 years. The baseline values of serum BPA were measured. Renal function was measured as eGFR calculated by the Chronic Kidney Disease Epidemiology Collaboration creatinine-cystatin C equation. Development of CKD was defined as eGFR < 60 mL/min/1.73 m(2) at the last follow-up. Regression models were used to analyze the associations of serum BPA with the change in eGFR and the risk of CKD development. Baseline serum BPA concentration was 0.40 (0.17, 1.40) ng/mL. Duration of T2D, baseline waist circumference, systolic blood pressure, diastolic blood pressure, fasting plasma glucose, and serum BPA level were significantly negatively associated with the annual change and percentage change in eGFR. After adjusting for clinical factors, baseline serum BPA level had a significant negative association with the annual change in eGFR (β = -0.371, P < 0.001) and p...Continue Reading

References

Jan 5, 2011·The Journal of Clinical Endocrinology and Metabolism·Eleni KandarakiEvanthia Diamanti-Kandarakis
Mar 3, 2012·Clinical Journal of the American Society of Nephrology : CJASN·Hien PhamIan H de Boer
May 31, 2012·Environmental Health Perspectives·Anoop ShankarCharumathi Sabanayagam
Jul 6, 2012·The New England Journal of Medicine·Lesley A InkerUNKNOWN CKD-EPI Investigators
Sep 27, 2012·Current Opinion in Nephrology and Hypertension·Carmine ZoccaliFrancesca Mallamaci
May 21, 2013·Journal of the American Society of Nephrology : JASN·Eugene P RheeRobert E Gerszten
Jul 4, 2013·Human & Experimental Toxicology·N Yıldız, N Barlas
Sep 3, 2013·International Journal of Nephrology·Emilio González-ParraJesus Egido
Oct 3, 2013·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Kahkashan RashidParames C Sil
Apr 3, 2014·Environmental Health : a Global Access Science Source·Laura N VandenbergTracey J Woodruff
Apr 12, 2014·Journal of Diabetes·Wichai AekplakornBoonsong Ongphiphadhanakul
Apr 12, 2014·International Journal of Obesity : Journal of the International Association for the Study of Obesity·Y SongQ Sun
May 9, 2014·Journal of Cellular Physiology·Nuria Olea-HerreroRicardo J Bosch
Jun 4, 2014·JAMA : the Journal of the American Medical Association·Josef CoreshAndrew S Levey
Oct 10, 2014·Acta Diabetologica·Giuseppe Pugliese
Dec 21, 2014·Journal of the American Society of Nephrology : JASN·Li FanLesley A Inker

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Citations

Nov 7, 2017·Journal of Developmental Origins of Health and Disease·P NuñezJ Arguelles
Feb 25, 2019·The Journal of Endocrinology·Shiyun TongQifu Li
Nov 22, 2018·The Journal of Clinical Endocrinology and Metabolism·Alessandro MengozziAnna Solini
Oct 24, 2018·Endocrine Connections·Maurício Martins Da SilvaAndrea C F Ferreira
Oct 19, 2017·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Linqiang MaShumin Yang
Jan 23, 2020·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Ruolin LiAijun Chen
May 4, 2020·Environmental Science and Pollution Research International·Muhammad Ejaz Ul HaqKanwal Rehman
Feb 6, 2021·The Science of the Total Environment·Hongli NieMeian He
Aug 7, 2021·Biomolecules·Rafael Moreno-Gómez-ToledanoRicardo J Bosch
Aug 22, 2021·Environmental Research·Christopher J MartyniukLorraine Chalifour

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