Serum CETP concentration is not associated with measures of body fat: The NEO study

Atherosclerosis
Lisanne L BlauwPatrick C N Rensen

Abstract

Adipose tissue has been postulated to contribute substantially to the serum cholesteryl ester transfer protein (CETP) pool. However, in a recent large cohort study waist circumference was not associated with plasma CETP. The aim of the present study was to further examine associations of accurate measures of body fat and body fat distribution with serum CETP concentration. In this cross-sectional analysis of the Netherlands Epidemiology of Obesity study, we examined in 6606 participants (aged 45-65 years) the associations of total body fat, body mass index (BMI), waist circumference, waist-to-hip ratio (WHR), abdominal subcutaneous (aSAT) and visceral adipose tissue (VAT) assessed with magnetic resonance imaging (n = 2547) and total and trunk fat mass assessed with dual-energy X-ray absorptiometry (n = 909) with serum CETP concentration. Regression models were adjusted for age, ethnicity, sex, dietary intake of fat and cholesterol, physical activity, smoking and menopausal status. Mean (SD) age was 56 (6) years and BMI 26.3 (4.4) kg/m(2), 56% were women. Mean serum CETP concentration was 2.47 μg/mL. The difference in serum CETP was 0.02 μg/mL (95%CI: -0.01, 0.05) per SD total body fat (8.7%), and 0.02 μg/mL (0.00, 0.04) per SD ...Continue Reading

References

Sep 1, 1991·American Journal of Public Health·E L Korn, B I Graubard
May 1, 1995·American Journal of Public Health·R RoubenoffP W Wilson
Dec 16, 1994·Clinica Chimica Acta; International Journal of Clinical Chemistry·V Guyard-DangremontC Lallemant
Jan 14, 1998·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·K N FraynL K Summers
Aug 24, 1999·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·T NagayaM Kawai
Feb 23, 2000·The Journal of Clinical Investigation·Y Luo, A R Tall
Dec 19, 2003·Journal of Clinical Epidemiology·G C Wanda Wendel-VosDaan Kromhout
Aug 1, 1997·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·J C Seidell, C Bouchard
Jul 25, 2006·Obesity·Themistoklis TzotzasLaurent Lagrost
May 26, 2007·Journal of Lipid Research·Caroline C van der HoogtPatrick C N Rensen
Dec 5, 2008·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Stephen A HarrisonBrent A Neuschwander-Tetri
Feb 10, 2009·Lipids·Faidon MagkosBettina Mittendorfer
Oct 15, 2009·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Kittichai PromratRena R Wing
May 25, 2010·Atherosclerosis·Shoko HonzumiNaoki Terasaka
May 19, 2011·International Journal of Obesity : Journal of the International Association for the Study of Obesity·J Gómez-AmbrosiG Frühbeck
Nov 7, 2012·The New England Journal of Medicine·Gregory G SchwartzUNKNOWN dal-OUTCOMES Investigators
Jan 18, 2013·European Journal of Clinical Nutrition·A Böhm, B L Heitmann
Apr 12, 2013·European Journal of Epidemiology·Renée de MutsertFrits Richard Rosendaal
Jul 16, 2015·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Yanan WangPatrick C N Rensen

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

International Journal of Obesity : Journal of the International Association for the Study of Obesity
K A ShawA J Venn
Journal of the American Geriatrics Society
Radboud M MarijnissenRichard C Oude Voshaar
© 2021 Meta ULC. All rights reserved