PMID: 6977424Dec 1, 1981Paper

Serum CK-MB activity during and after aortocoronary bypass surgery

Clinical Biochemistry
B C MortonW J Keon

Abstract

Frequent serum sampling of CK-MB and total CK levels was carried out in 100 patients during and up to 48 hours following aortocoronary bypass surgery. Using an ion exchange chromatography method for CK-MB determination, significantly higher serum CK-MB levels (peak 46.1 +/- 5.2 cf. 31.3 +/- 2.2 u/L), but not total CK levels were present 6 to 16 hours postoperatively in those with new Q waves in the ECG. Serum levels of CK-MB in those patients with uncomplicated surgery were defined. New post-operative Q waves were seen in only one half of cases with frankly abnormal CK-MB curves and seriously underestimated the incidence of perioperative infarction. Peak levels of CK-MB in patients with new Q waves occurred within 16 hours of surgery suggesting that infarction is usually an intraoperative or early post-operative event.

References

Oct 1, 1979·The American Journal of Cardiology·H R BaurF L Gobel
Apr 1, 1978·American Heart Journal·R Roberts, B E Sobel
Jul 1, 1979·The American Journal of Cardiology·W E ShellM Burnam
Nov 1, 1975·Circulation·R RobertsB E Sobel
Jan 1, 1973·Circulation·D L BrewerA G Bartel
Feb 14, 1974·The New England Journal of Medicine·M M BassanH J Swan
Nov 1, 1971·American Heart Journal·H N HultgrenW W Angell

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