PMID: 5902390Jan 28, 1966

Serum concentration: effects on cycle and x-ray sensitivity of mammalian cells

Science
G M Hahn, M A Bagshaw

Abstract

If the content of serum in the culture medium of exponentially growing Chinese hamster cells is below optimum (15 percent), the doubling time and the resistance to x-irradiation of the cells are increased. In synchronously dividing populations the increase in doubling time is primarily caused by increase in duration of the postmitotic (G(1)) phase of the cells; this phase is relatively radiation resistant. The response of the cells growing synchronously is related quantitatively to the response of the cells dividing randomly.

Citations

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Related Concepts

Blood
Carbon Isotopes
Cell Division Phases
Cricetus
Effects of Radiation
Nuclear Track Detection
Thymidine
Culture Techniques

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