Serum concentrations of nitric oxide, tumor necrosis factor (TNF)-alpha and TNF soluble receptors in women with overweight and obesity

Metabolism: Clinical and Experimental
Magdalena Olszanecka-GlinianowiczA Zurakowski

Abstract

The aims of the present study was to examine how overweight and obesity affect serum concentrations nitric oxide (NO) metabolites and to determine whether there is association between serum concentrations tumor necrosis factor (TNF)-alpha and TNF soluble receptors (sTNF-R) in subjects with overweight and obesity. The study groups involved 154 women: 102 obese (81 obese with body mass index [BMI] 30 to 40 kg/m2 and 21 obese with BMI > 40 kg/m2), 24 overweight patients, and 28 lean controls. Serum concentrations of NO metabolites and of TNF-alpha and its soluble receptors (sTNF-R1, sTNFR-2) were measured by enzyme-linked immunosorbent assay (ELISA) kits. Serum concentration of insulin was measured by radioimmunoassay (RIA). Plasma glucose, cholesterol, high-density lipoprotein (HDL)-cholesterol, and triglicerydes were determined by enzymatic procedure. Body composition was determined by impedance analysis using Bodystat (Douglas, British Isles). Serum concentrations of NO in the overweight group (35.1 +/- 12.1 micromol/L) and the obese groups with BMI 30 to 40 kg/m2 (32.8 +/- 9.3 micromol/L) and with BMI greater than 40 kg/m2 (33.3 +/- 8.5 micromol/L) were significantly higher when compared to controls (28.2 +/- 8.1 micromol/L): ...Continue Reading

References

Jan 1, 1995·European Journal of Haematology·A Diez-RuizD Fuchs
Aug 13, 1994·BMJ : British Medical Journal·P Vallance, J Collier
May 24, 1996·Biochemical and Biophysical Research Communications·C RibiereY Giudicelli
Dec 17, 1997·The Journal of Clinical Endocrinology and Metabolism·V Mohamed-AliS W Coppack
Dec 31, 1997·The Journal of Clinical Investigation·T Michel, O Feron
Apr 17, 1998·Cancer Metastasis Reviews·D A Geller, T R Billiar
Jan 7, 1999·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·H HaunerF Hube
Dec 22, 1999·The American Journal of Physiology·V Mohamed-AliS W Coppack
Aug 15, 2000·Annual Review of Nutrition·C HolmJ A Contreras
Jan 11, 2000·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·B Zahorska-MarkiewiczA Zurakowski
Jul 6, 2001·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·M RydénK Andersson
Jun 18, 2003·Journal of Endocrinological Investigation·G NicolettiK Esposito

❮ Previous
Next ❯

Citations

Jan 17, 2008·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·M KoziołekS Giedrys-Kalemba
Dec 4, 2008·Obesity Surgery·Eva SoláAntonio Hernández-Mijares
Mar 3, 2011·International Journal of Obesity : Journal of the International Association for the Study of Obesity·S-M Kuo, M M Halpern
Jul 16, 2010·Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research·Akira SekikawaUNKNOWN ERA JUMP Study group
Mar 1, 2008·PPAR Research·Cadence E MingeRobert J Norman
Sep 6, 2007·The Journal of Clinical Investigation·Yihai Cao
Aug 16, 2012·The Journal of Clinical Endocrinology and Metabolism·Rachana ShahMuredach P Reilly
Apr 19, 2012·Journal of Periodontology·Özgün ÖzçakaNurcan Buduneli
Jul 6, 2014·Oxidative Medicine and Cellular Longevity·Gregorio CaimiEugenia Hopps
Nov 3, 2009·Endocrine Research·Qihuan LvXiaohui Zhou
Mar 1, 2009·Expert Opinion on Medical Diagnostics·Irene Meester, Juan Manuel Solis-Soto
Aug 3, 2010·Veterinary Immunology and Immunopathology·Anouk Lavoie-LamoureuxJean-Pierre Lavoie
Jun 29, 2010·Metabolism: Clinical and Experimental·Magdalena Olszanecka-GlinianowiczBarbara Zahorska-Markiewicz
Sep 29, 2009·Clinical Biochemistry·Asghar GhasemiFereidoun Azizi
Dec 17, 2015·Journal of Clinical Laboratory Analysis·Serkan DoganSebnem Gursoy
Jul 10, 2007·Metabolism: Clinical and Experimental·Barbara Zahorska-MarkiewiczAnna Skorupa
Jan 17, 2007·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Magdalena Olszanecka-GlinianowiczKatarzyna Klimek
Feb 12, 2009·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·F BoesingE A M Moreira
Mar 18, 2016·Nutrition & Metabolism·Zahra BahadoranFereidoun Azizi
May 12, 2006·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·María-Pía de la MazaMireya Fernández
Aug 24, 2013·International Journal of Endocrinology·Agnieszka Zak-GołąbMagdalena Olszanecka-Glinianowicz
Jul 10, 2009·Mediators of Inflammation·Magdalena Olszanecka-GlinianowiczPiotr Dabrowski
Jan 23, 2010·Metabolism: Clinical and Experimental·Jae Hoon MoonBong-Soo Cha
Dec 30, 2014·Journal of the American Society of Hypertension : JASH·Piotr KocelakJerzy Chudek
Jul 8, 2009·Diabetes·Rachana ShahMuredach P Reilly
Nov 20, 2012·Diabetes & Metabolic Syndrome·Gregorio CaimiMaurizio R Averna
Apr 16, 2019·International journal for vitamin and nutrition research. Internationale Zeitschrift für Vitamin- und Ernährungsforschung. Journal international de vitaminologie et de nutrition·Seyed Mohammad MousaviHamed Kord Varkaneh

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.