PMID: 6989485Apr 15, 1980Paper

Serum copper levels in non-Hodgkin's lymphoma

I Shah-ReddyC R Bishop


Levels of serum copper in 34 patients with adult non-Hodgkin's lymphoma at different phases of the disease have been studied. All of the patients were evaluated with complete blood counts, sedimentation rate, gallium scintigraphy, liver and bone marrow biopsies, lymph node biopsy, and laparoscopy. The level of serum copper was significantly elevated in non-responding or relapsing patients (mean 191.06 micrograms/dl), and correlated with the estimated tumor burden. Serum copper levels within normal range were found in patients in complete remission (mean 114.76 micrograms/dl). Age- and sex-matched normal controls also showed serum copper levels within normal range (mean 112.81 micrograms/dl). It is proposed that serial measurements of serum copper level may be of use in: (1) monitoring the remission status of patients with non-Hodgkin's lymphoma, (2) detecting early relapse of non-Hodgkin's lymphoma, and (3) contrary to previous reports by Hrgovcic et al., the level of serum copper seems to be related to the disease activity of histiocytic lymphoma.


Feb 1, 1973·Cancer·C F TessmerJ Wilbur
Jan 1, 1967·American Journal of Obstetrics and Gynecology·S O'Reilly, M Loncin
Jan 1, 1964·Scandinavian Journal of Haematology·K B JENSENC J ANDERSEN


Oct 30, 1987·Clinica Chimica Acta; International Journal of Clinical Chemistry·D M Goldberg, D Brown
Apr 1, 1985·The Science of the Total Environment·S G KrishnaM Nair
Jan 1, 1988·Nutrition and Cancer·H P FieldA V Simmons
Mar 1, 1983·Journal of Surgical Oncology·A BirdiS S Gambhir
Feb 12, 2020·International Journal of Molecular Sciences·Silvia BaldariGabriele Toietta
Mar 1, 1984·Scandinavian Journal of Haematology·I ShahD Kessel

Related Concepts

Diffuse Large B-Cell Lymphoma

Related Feeds

B-Cell Lymphoma

B-cell lymphomas include lymphomas that affect B cells. This subtype of cancer accounts for over 80% of non-Hodgkin lymphomas in the US. Here is the latest research.

Blood And Marrow Transplantation

The use of hematopoietic stem cell transplantation or blood and marrow transplantation (bmt) is on the increase worldwide. BMT is used to replace damaged or destroyed bone marrow with healthy bone marrow stem cells. Here is the latest research on bone and marrow transplantation.