Serum creatine kinase activity varies with ovulatory status in regularly exercising, premenopausal women

Hormone Research
Heather S ThompsonMary Jane De Souza

Abstract

The clinical complications associated with an unopposed estrogen environment and luteal phase defects observed in exercising women prompted the examination of the relationship of exercise and endogenous ovarian steroids with serum creatine kinase (CK) activity. Subjects (n = 34) were classified into three groups according to their exercise and menstrual status, sedentary and exercising ovulatory groups (SedOvul, ExOvul), and an exercising amenorrheic group (ExAmen). Daily urine samples were collected to assess urinary ovarian steroid exposure and menstrual status. Serum CK activity was assayed in each menstrual cycle of all subjects. Exercise increased serum CK activity in all exercising subjects (p < 0.01), but the increase was greater in amenorrheic women compared to ovulatory women (SedOvul: 33.0 +/- 3.4; ExOvul: 43.7 +/- 4.1; ExAmen: 54.4 +/- 3.6, p < 0.05). When the ovulatory women were further divided into those with normal steroid production (ExOvul subgroup) and those with a suppressed progesterone luteal phase environment (ExLPD), both the ExOvul (51.9 +/- 5.4 IU/l) subgroup and ExAmen group had higher serum CK activity (p < 0.05) than the ExLPD (36.6 +/- 5.2 IU/l) subjects or the sedentary controls. These data demonst...Continue Reading

References

Feb 1, 1976·Endocrinology·A J HsuehJ H Clark
Apr 1, 1976·Fertility and Sterility·G S Jones
Jan 11, 1992·Reproductive Toxicology·J S KesnerE F Krieg
Sep 1, 1991·Journal of Applied Physiology·J H Van der MeulenJ Drukker
Jun 1, 1991·The Journal of Clinical Endocrinology and Metabolism·I Z BeitinsB A Bullen
Jun 1, 1990·Proceedings of the Society for Experimental Biology and Medicine·R E Allen, L L Rankin
Feb 1, 1989·The Journal of Clinical Endocrinology and Metabolism·A B LoucksS S Yen
Jan 1, 1986·Breast Cancer Research and Treatment·P Mauvais-JarvisA Gompel
Jul 1, 1987·Sports Medicine·T D Noakes
Dec 1, 1985·Medicine and Science in Sports and Exercise·M A RogersF S Apple
Sep 1, 1965·British Heart Journal·F G WarburtonA C Wright
Jan 1, 1983·Medicine and Science in Sports and Exercise·P M Tiidus, C D Ianuzzo
Jan 1, 1981·Journal of Receptor Research·C SumidaJ R Pasqualini
Apr 1, 1995·International Journal of Sports Medicine·J KomulainenV Vihko
Apr 1, 1996·Journal of Assisted Reproduction and Genetics·R BabalioğluF Cizmecioğlu
Jul 1, 1996·Medicine and Science in Sports and Exercise·K M WintersB L Lasley
Feb 1, 1997·Biochemical Society Transactions·P R Bär, G J Amelink
Dec 1, 2000·Canadian Journal of Applied Physiology = Revue Canadienne De Physiologie Appliquée·M G ArnettC M Schneider
Sep 25, 2001·Journal of Applied Physiology·N StupkaS M Phillips
Jan 31, 2002·Sports Medicine·Becky Kendall, Roger Eston
Mar 22, 2002·Clinical and Experimental Pharmacology & Physiology·David Cameron-Smith
Nov 21, 2002·American Journal of Physiology. Endocrinology and Metabolism·N SantoroG Weiss
Oct 23, 2003·Annual Review of Cell and Developmental Biology·Paul L McNeil, Richard A Steinhardt
Jul 3, 2004·Human Reproduction Update·Mary Jane De Souza, Nancy I Williams
Sep 29, 2004·Acta Physiologica Scandinavica·H YanoS Kira

❮ Previous
Next ❯

Citations

Jan 31, 2012·Journal of Nutrition and Metabolism·Marianne F BairdGordon F Bickerstaff
Jun 21, 2018·Journal of Human Kinetics·Mateusz RadojewskiJoanna Karolkiewicz
Jul 4, 2009·Journal of Applied Physiology·Christina M Dieli-ConwrightE Todd Schroeder
Mar 17, 2015·Journal of Strength and Conditioning Research·Danguolė SatkunskienėDonatas Rauktys
Aug 18, 2020·Scandinavian Journal of Medicine & Science in Sports·Svein Ivar Bekkelund

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2021 Meta ULC. All rights reserved