Serum creatinine and alkaline phosphatase levels are associated with severe chronic periodontitis

Journal of Periodontal Research
A L CaúlaR G Fischer

Abstract

Periodontitis may alter systemic homeostasis and influence creatinine and alkaline phosphatase levels. Therefore, the aim of this study was to evaluate the relationship between severe chronic periodontitis and serum creatinine and alkaline phosphatase levels. One hundred patients were evaluated, 66 with severe chronic periodontitis (test group) and 34 periodontally healthy controls (control group). Medical, demographic and periodontal parameters were registered. Blood sample was collected after an overnight fast and serum creatinine and alkaline phosphatase levels were determined. There were significant differences between test and control groups in ethnicity, gender and educational level (p < 0.05). Patients with periodontitis showed a lower mean creatinine level (p < 0.05) and higher mean alkaline phosphatase level (p < 0.001) than the control group. There were significant correlations between periodontal parameters and serum creatinine and alkaline phosphatase levels. Severe chronic periodontitis was associated to lower creatinine and higher alkaline phosphatase levels.

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Citations

Apr 19, 2017·Journal of Clinical Periodontology·Luiz Felipe C FrançaDaniel F P Vasconcelos
Sep 1, 2018·Oral Diseases·Emrah AnbarciogluRamis Colak
Jun 11, 2020·Clinical Oral Investigations·Ana R O MoreiraCecilia C C Ribeiro
Feb 8, 2019·Critical Reviews in Microbiology·Aditi Chopra, Karthik Sivaraman

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