Serum endothelial cell specific molecule-1 (endocan) levels in patients with obstructive sleep apnea

Biomarkers in Medicine
Zuleyha BingolEsen Kıyan

Abstract

To investigate the level of endothelial cell specific molecule-1 (endocan) in obstructive sleep apnea (OSA). Study group included subjects with OSA. Control group included subjects who had no OSA on polysomnography and nonobese healthy subjects from population who had no OSA symptoms. Endocan levels of OSA and non-OSA subjects were compared. Totally 106 individuals (63 OSA, 43 non-OSA) were included. Endocan levels were higher in OSA subjects than controls (1.25 ± 0.4 ng/ml vs 0.93 ± 0.3 ng/ml, p < 0.001). Endocan levels were correlated with BMI (r = 0.456, p < 0.001) and daytime PaO2 (r = -0.266, p < 0.042). In linear regression analysis there was no factor related to endocan level. Serum endocan is significantly higher in OSA. Further studies should be performed to better understand the relationship between endocan and OSA.

References

Jul 1, 1967·British Journal of Preventive & Social Medicine·T Khosla, C R Lowe
Apr 29, 1993·The New England Journal of Medicine·T YoungS Badr
Aug 23, 1996·The Journal of Biological Chemistry·P LassalleA B Tonnel
Feb 24, 2001·American Journal of Respiratory and Critical Care Medicine·E ShaharJ M Samet
Sep 7, 2001·The Journal of Immunology : Official Journal of the American Association of Immunologists·D BéchardP Lassalle
Jun 5, 2003·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·M WellnerA M Sharma
Jul 14, 2004·Circulation·Apoor S GamiVirend K Somers
Jan 21, 2006·Critical Care Medicine·Arnaud ScherpereelPhilippe Lassalle
Feb 16, 2006·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·J JankeA M Sharma
Aug 11, 2006·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Bogdan Dragos GrigoriuPhilippe Lassalle
Oct 2, 2008·The European Respiratory Journal·P LévyC Ribuot
Aug 25, 2009·PloS One·Jean-Christian BorelJean-Louis Pepin
Jan 28, 2010·Histopathology·Xavier LeroyPhilippe Lassalle
Apr 13, 2010·Annals of Surgical Oncology·Ni LiuJia-fu Ji
Oct 1, 2011·Journal of Critical Care·Mark E MikkelsenJason D Christie
Oct 11, 2013·Clinical Chemistry and Laboratory Medicine : CCLM·Shang-Jyh KaoMing-Hsien Chien
Nov 2, 2013·Journal of the American Academy of Dermatology·Ilknur BaltaYasemin Gulcan Kurt
Feb 11, 2014·Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis·Aygül GüzelNaci Murat

❮ Previous
Next ❯

Citations

Nov 20, 2016·Respirology : Official Journal of the Asian Pacific Society of Respirology·Chris D TurnbullMalcolm Kohler
Mar 5, 2021·Immunity & Ageing : I & a·Pavel BorskyLenka Borska

❮ Previous
Next ❯

Methods Mentioned

BETA
enzyme-linked immunosorbent assay

Software Mentioned

SPSS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Pediatric Pulmonology
M Klein, L G Reynolds
Arquivos de neuro-psiquiatria
Michele Dominici, Marleide da Mota Gomes
© 2021 Meta ULC. All rights reserved