Abstract
Allergic rhinitis is a common disease, in which some patients will deteriorate or develop asthma. It is important to characterize these patients, thereby offering the possibility for prevention. This study evaluated eosinophil parameters as potential indicators of deteriorating allergic airway disease. The subjects of the study included all patients who suffered seasonal allergic rhinitis and had participated in a study 6 years earlier, in which blood eosinophils, serum eosinophil cationic protein (ECP) serum eosinophil peroxidase (EPO), nasal lavage ECP and nasal lavage EPO levels were measured. Patients in the present study were interviewed on occurrence of rhinitis symptoms during the last season, rhinitis outside season, asthma-like symptoms and asthma diagnosis, and were skin-prick tested for common aeroallergens. Eosinophil parameters from the study 6 years earlier were then tested for the ability to predict occurrence of new allergies, worsening of rhinitis and occurrence of asthma. Forty-four patients participated in the study. In four patients seasonal rhinitis symptoms had deteriorated, 10 had experienced perennial rhinitis symptoms, 14 reported asthma-like symptoms and seven had been diagnosed with asthma. Thirteen h...Continue Reading
References
Aug 1, 1976·The Journal of Allergy and Clinical Immunology·G W Hagy, G A Settipane
Feb 1, 1992·Acta Paediatrica·O LinnaM Lukin
Jan 1, 1994·Allergy Proceedings : the Official Journal of Regional and State Allergy Societies·R J SettipaneG A Settipane
Nov 1, 1996·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·L P NielsenR Dahl
Jan 1, 1997·International Archives of Allergy and Immunology·M Hoshino, Y Nakamura
Mar 1, 1997·Allergy·J Danielsson, M Jessen
Sep 4, 1998·Allergy and Asthma Proceedings·W A GreisnerG A Settipane
Nov 5, 1998·Allergy and Asthma Proceedings·W A GreisnerG A Settipane
Mar 11, 1999·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·M SimolaH Malmberg
Sep 1, 1999·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·P VengeA Trulson
Dec 22, 1999·Allergy·A LinnebergT Jørgensen
Mar 4, 2000·The European Respiratory Journal·R PolosaN Crimi
Sep 1, 2000·The European Respiratory Journal·R LeighF E Hargreave
Sep 16, 2000·American Journal of Respiratory and Critical Care Medicine·P P PlaschkeB Järvholm
May 3, 2001·Allergy and Asthma Proceedings·P PohunekJ Zikán
Jun 5, 2001·Pediatric Pulmonology·M PifferiG Baldini
Jul 13, 2001·The Journal of Allergy and Clinical Immunology·D P Skoner
Nov 15, 2001·The Journal of Allergy and Clinical Immunology·J BousquetUNKNOWN World Health Organization
Mar 19, 2002·The Journal of Allergy and Clinical Immunology·Stefano GuerraRobert A Barbee
Jan 18, 2003·The Journal of Allergy and Clinical Immunology·Elizabeth A Becky KellyNizar N Jarjour
Jun 8, 2006·International Archives of Allergy and Immunology·Johsuke HaraKazuo Kasahara
Citations
Mar 9, 2011·Inflammation·Mary KämpeMarie Carlson
Aug 7, 2013·Current Allergy and Asthma Reports·Zuzana DiamantLeif Bjermer
Nov 2, 2013·Journal of Clinical Gastroenterology·Christoph SchlagMonther Bajbouj
Jul 31, 2013·The Journal of Allergy and Clinical Immunology·Andrei MalinovschiChrister Janson
Sep 1, 2015·Alimentary Pharmacology & Therapeutics·C SchlagM Bajbouj
May 13, 2014·The Tohoku Journal of Experimental Medicine·Jae-Woo JungSeong-Wook Sohn
Dec 19, 2018·Intractable & Rare Diseases Research·Ghada AAbdullateef A Alzolibani
Jun 13, 2009·Growth Factors·Takayuki FukudaMasaharu Seno
Aug 7, 2013·Clinical Pharmacology and Therapeutics·C-P Milne
Oct 17, 2017·Frontiers in Medicine·Emma DoranJoseph R Arron
Jul 4, 2018·Inflammation·Hee-Yun KimHyun-Ja Jeong
Jan 20, 2017·Journal of Inflammation·Shaoqing YuRongming Ge
Sep 1, 2017·Genome Biology and Evolution·Matthew F BarberNels C Elde
Jan 14, 2010·Current Opinion in Otolaryngology & Head and Neck Surgery
Dec 23, 2009·Current Opinion in Allergy and Clinical Immunology