PMID: 2498215Apr 1, 1989Paper

Serum factors stimulate the motility of human spermatozoa

International Journal of Andrology
E AkerlöfA Pousette

Abstract

Motile human sperm were collected from a Percoll gradient and the effects on sperm motility of human serum, various serum fractions, follicular fluid and seminal plasma were assessed. In culture medium alone (RPMI-1640) sperm motility was lost after about 5 h. The addition of male blood serum both enhanced sperm motility and prolonged viability very significantly. Albumin, seminal plasma and follicular fluid all stimulated sperm motility but to a much lesser extent than did blood serum. No difference was noted between male serum or female serum which had been collected during the follicular or luteal phases of hormone-stimulated cycles and which contained high levels of oestradiol. Serum fractions obtained by separation on Sephacryl S-300 column were tested for their ability to enhance sperm motility. The most pronounced effect, much superior to that achieved by the albumin fraction, was obtained by a fraction with a molecular weight of around 200 kD. In conclusion, certain factors in human serum, which are different from albumin, strongly support sperm motility. The high serum concentrations of oestradiol resulting from hormone stimulation for in-vitro fertilization do not invalidate the use of serum from the same patient duri...Continue Reading

References

Oct 1, 1987·International Journal of Andrology·E AkerlöfA Pousette
Oct 1, 1986·International Journal of Andrology·A PousetteB Fredricsson

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Citations

Apr 1, 1992·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·S L LeeY H Wei
Aug 1, 1990·International Journal of Andrology·L RosenborgB Fredricsson
Feb 1, 1991·International Journal of Andrology·E de Lamirande, C Gagnon
Feb 1, 1993·Pharmacology & Toxicology·B FredricssonR Westerholm
Jul 6, 2010·Journal of Proteomics·Arlindo A MouraGary J Killian
Oct 20, 2012·Proteomics·Keren ByrneMichael K Holland
Jan 1, 1993·Scandinavian Journal of Clinical and Laboratory Investigation. Supplementum·A PousetteE Akerlöf
Sep 25, 2018·Reproduction in Domestic Animals = Zuchthygiene·Maria Júlia B BezerraArlindo A Moura
Mar 1, 1991·Archives of Andrology·H T ChaoC Y Hong
Jan 1, 1996·Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes·M I YousefM H Salem

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