PMID: 3321090Jan 1, 1986Paper

Serum fatty acids and coronary heart disease in Finnish populations

Progress in Lipid Research
T Nikkari

Abstract

Finland has one of the highest coronary heart disease (CHD) rates in the whole world, and within the country, the rates are higher in men and eastern Finland than in women and western Finland, respectively. The differences are not wholly explained by the 3 classical risk factors. Several cross-sectional and longitudinal studies suggest that the intake of dietary linoleate (18:2), as reflected in the composition of serum and tissue fatty acids, has an inverse association with CHD, although there are also studies with negative results. Our own retrospective study failed to show any differences in the fatty acid composition of serum CE, TG or PL between men who had died of CHD and age- and risk factor-matched controls, but the negative finding may be due to changes in the fatty acids during storage. Among Finnish populations, most serum CE fatty acids had highly significant correlations with those in other serum lipid fractions, adipose tissue and platelets, and they had good "tracking" for up to 4 yr. Serum CE and TG 18:2, and total omega 6 polyunsaturated fatty acids (PUFA) had strong correlations with dietary 18:2 and PUFA, and can thus be used in the evaluation of population differences in the intake of PUFA. CE fatty acids we...Continue Reading

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Citations

Oct 1, 1987·Atherosclerosis·T MoilanenT Nikkari
Aug 2, 2005·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·Johan ArnlövHans Lithell
Mar 26, 2003·The British Journal of Nutrition·A M TullyM J Gibney
Feb 1, 1989·Annals of the Rheumatic Diseases·J JänttiH Isomäki
Nov 16, 2010·Scandinavian Journal of Gastroenterology·Tiina SolakiviSeppo Tapio Nikkari
Apr 25, 2009·Scandinavian Journal of Gastroenterology·Tiina SolakiviSeppo Tapio Nikkari
May 1, 1997·Arteriosclerosis, Thrombosis, and Vascular Biology·V V SalomaaG Myllylä
Apr 17, 2020·Nutrition Reviews·João Tomé-CarneiroAlberto Dávalos

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