Serum folate and vitamin B12 status in young Brazilian children

Public Health Nutrition
Lara Ls SilvaENFAC Working Group

Abstract

To assess the nutritional status of folate and vitamin B12 with anaemia in young children. A cross-sectional study was conducted at the primary health-care centres of four Brazilian cities. Folate and vitamin B12 were assessed by fluoroimmunoassay. Multilevel Poisson regression models were used to explore the association of folate and vitamin B12 status in relation to anaemia in young children. Brazil.ParticipantsChildren (n 460) aged 11 to 15 months. The median (interquartile range) of serum folate was 39·7 (28·8-55·3) nmol/l and only four children presented with folate deficiency (<10 nmol/l). Surprisingly, 30·9 % of children presented with serum folate concentrations above the upper limit of detectable values by the commercial kit used for analysis. The frequency of vitamin B12 deficiency (<148 pmol/l) was 15 % and it was inversely associated with the highest tertile of serum folate concentrations (P<0·001). Having high serum folate concentration (≥50·1 nmol/l) and vitamin B12≥148 pmol/l was associated with lower frequency of anaemia in these children (prevalence ratio=0·53; 95% CI 0·30, 0·92). High frequency of elevated serum concentration of folate was found among young Brazilian children and 15 % of them had vita...Continue Reading

References

Apr 1, 1988·Journal of Biological Standardization·P Sizaret
Aug 20, 2008·Food and Nutrition Bulletin·Lindsay H Allen
Aug 20, 2008·Food and Nutrition Bulletin·Bruno de Benoist
Mar 18, 2010·International Journal of Pediatric Obesity : IJPO : an Official Journal of the International Association for the Study of Obesity·M de Onis, T Lobstein
May 29, 2010·Journal of Inherited Metabolic Disease·Anne-Lise Bjørke-Monsen, Per Magne Ueland
Apr 27, 2012·Salud pública de México·Lucía Cuevas-NasuSalvador Villalpando
Jul 18, 2014·Revista brasileira de hematologia e hemoterapia·Jéssica Carrilho BrittoElvira Maria Guerra-Shinohara
Jan 17, 2015·Public Health Nutrition·Fernanda CobayashiUNKNOWN ACTION Study Team
Jul 15, 2015·Journal of Public Health·Cynthia K ColapintoMark S Tremblay
May 2, 2016·Biochimie·Jacob Selhub, Irwin H Rosenberg
Jul 28, 2016·The British Journal of Nutrition·Caroline Nicola SangalliMárcia Regina Vitolo
Nov 24, 2016·Molecular Aspects of Medicine·Ligi Paul, Jacob Selhub
Jan 21, 2017·Nutrients·Bernadette N Ng'enoMaria Elena D Jefferds
Jul 1, 2017·Nature Reviews. Disease Primers·Ralph GreenChittaranjan Yajnik
Feb 17, 2018·Annals of the New York Academy of Sciences·Greg S Garrett, Lynn B Bailey

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