PMID: 15233314Jul 6, 2004Paper

Serum fructosamine and colorectal adenomas

European Journal of Epidemiology
G MisciagnaINTEROSP Group

Abstract

The relationship of glucose in the blood with colorectal adenoma or cancer is not clear. Fructosamine, equivalent to total serum glycated proteins, is a marker of blood glucose levels in the previous 3 weeks. We evaluated in a case-control study the association between fructosamine and colorectal adenoma, a precursor of colorectal cancer. Cases were subjects with the first occurrence of one or more histologically confirmed colorectal adenomatous polyps removed after a complete colonoscopy (153 cases), and controls were subjects with normal colonoscopy performed in the same endoscopy units during the same period (84 controls). Serum fructosamine was measured by a colorimetric method. Unconditional multiple logistic regression was used for statistical analysis. We found that in non-diabetic subjects the risk of colorectal adenoma increased with the level of fructosamine, and the odds ratio of colorectal adenoma in subjects with fructosamine levels higher than the median (270 microg/100 ml), in comparison with subjects with fructosamine lower than the median, was 2.3 (95% CI: 1.1-4.8). The risk of colorectal adenoma increased also with increasing levels of serum triglycerides and cholesterol, and decreased with increasing levels o...Continue Reading

Citations

Oct 14, 2008·Genes & Nutrition·G MisciagnaM Trevisan
Dec 15, 2010·Nutrition and Cancer·Rebecca L SedjoTim Byers
Feb 2, 2013·PloS One·Wahyu WulaningsihMieke Van Hemelrijck
Jan 22, 2011·World Journal of Gastroenterology : WJG·Maria NotarnicolaGiovanni Misciagna
May 23, 2014·Journal of the American Veterinary Medical Association·Kimberly M Pattullo, Beverly A Kidney
Mar 12, 2013·ISRN Oncology·Samy L Habib, Maciej Rojna
Jul 12, 2017·World Journal of Diabetes·Mirabella ZhaoJingbo Zhao
Nov 18, 2006·Cancer Causes & Control : CCC·Tetsuya OtaniShoichiro Tsugane
Mar 13, 2008·Oncology·Maria Gabriella CarusoGiovanni Misciagna
Aug 16, 2006·Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals·W K Al-DelaimyH B Bueno-de-Mesquita
May 20, 2015·Digestive Diseases and Sciences·Yoon Suk JungDong Il Park
Oct 10, 2014·Indian Journal of Clinical Biochemistry : IJCB·Azza M MohamedMohamed R Mohamed
Feb 13, 2008·The American Journal of Clinical Nutrition·Edward Giovannucci

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