Serum fructosamine concentration as an index of glycemia in cats with diabetes mellitus and stress hyperglycemia

Journal of Veterinary Internal Medicine
K L CrenshawR Nichols

Abstract

The purpose of this study was to evaluate fructosamine concentrations in clinically healthy cats, sick cats with stress hyperglycemia, and untreated diabetic cats to determine the usefulness of this test in diagnosing diabetes mellitus in cats, and in differentiating the disease from stress-induced hyperglycemia. In addition, we evaluated if the degree of glycemic control in cats treated for diabetes influenced their serum fructosamine concentrations. In the 14 sick cats with stress hyperglycemia, the median serum fructosamine concentration (269 mumol/L) was not significantly different from the median value in the 26 clinically normal cats (252 mumol/L). Two of the 14 cats with stress hyperglycemia (14.3%) had serum fructosamine concentrations above the upper limit of the reference range (175 to 400 mumol/L); on the basis of these results, the test specificity was calculated as 0.86. In 30 cats with untreated diabetes mellitus, the median serum fructosamine concentration was 624 mumol/L, markedly higher than the value in either the normal cats or the cats with stress hyperglycemia. All but 2 of the 30 untreated diabetic cats (6.7%) had serum fructosamine concentration above the upper limit of the reference range; on the basis o...Continue Reading

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Citations

Dec 4, 2008·Veterinary Research Communications·T SakoT Arai
Jun 1, 2005·Journal of Feline Medicine and Surgery·Jelena M E RisticBriän Catchpole
Jul 22, 2008·Journal of Feline Medicine and Surgery·Yaiza ForcadaLaura Blackwood
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Oct 5, 2021·Journal of Feline Medicine and Surgery·Chad F BermanJohan P Schoeman

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