PMID: 41851Sep 1, 1979

Serum gamma-glutamyltransferase isoenzymes in extrahepatic biliary obstruction

Journal of Clinical Pathology
P R WenhamH G Sammons

Abstract

The gamma-glutamyltransferase isoenzymes in the sera of patients with extrahepatic biliary obstruction have been studied, using electrophoretic, gel filtration, and ultracentrifugation techniques, and compared with those present in normal sera. Five isoenzymes were shown to exist in patients' sera, three of which were not demonstrated in normal sera. The observations are discussed in relation to the influence of biliary regurgitation and the possible solubilisation of membrane-bound enzymes. The results are compared with those of previous studies on alkaline phosphatase.

References

Apr 27, 1981·Clinica Chimica Acta; International Journal of Clinical Chemistry·P R WenhamA F Smith
Mar 19, 1981·Clinica Chimica Acta; International Journal of Clinical Chemistry·N E Huseby
Sep 1, 1982·Clinica Chimica Acta; International Journal of Clinical Chemistry·N E Huseby
Sep 1, 1982·Clinica Chimica Acta; International Journal of Clinical Chemistry·N E Huseby
Sep 30, 1982·Clinica Chimica Acta; International Journal of Clinical Chemistry·P R WenhamA F Smith
Aug 31, 1984·Clinica Chimica Acta; International Journal of Clinical Chemistry·P R WenhamA F Smith
Dec 29, 1984·Clinica Chimica Acta; International Journal of Clinical Chemistry·D RatanasavanhG Siest

Citations

Feb 10, 1978·Biochimica Et Biophysica Acta·N E Huseby
Jul 1, 1978·Journal of Clinical Pathology·P R WenhamH G Sammons
Sep 1, 1978·Clinica Chimica Acta; International Journal of Clinical Chemistry·N E Huseby, T Vik
Aug 4, 1975·Clinica Chimica Acta; International Journal of Clinical Chemistry·O HetlandT Gerner
Dec 15, 1977·Clinica Chimica Acta; International Journal of Clinical Chemistry·M E De BroeF Roels
Mar 24, 1975·Clinica Chimica Acta; International Journal of Clinical Chemistry·M E De BroeR J Wieme
Feb 1, 1972·Journal of Clinical Pathology·C P PriceH G Sammons
Aug 30, 1973·Clinica Chimica Acta; International Journal of Clinical Chemistry·A J KryszewskiD W Moss
Oct 12, 1973·Clinica Chimica Acta; International Journal of Clinical Chemistry·U B Seiffert, M Chaves
Sep 1, 1972·Gut·J B WhitfieldD W MOSS
Jan 24, 1973·Clinica Chimica Acta; International Journal of Clinical Chemistry·O Azzopardi, M F Jayle
May 1, 1974·Journal of Clinical Pathology·C P Price, H G Sammons
Aug 1, 1972·Clinica Chimica Acta; International Journal of Clinical Chemistry·S Miyazaki, M Okumura
Nov 1, 1966·Clinica Chimica Acta; International Journal of Clinical Chemistry·A Szewczuk
Mar 1, 1967·Clinica Chimica Acta; International Journal of Clinical Chemistry·M Orlowski, A Szczeklik
Oct 8, 1962·Biochimica Et Biophysica Acta·P FLODIN, J KILLANDER
Jan 1, 1963·The American Journal of Cardiology·N KRASNOWR GORLIN
Jan 6, 2010·Archivum Immunologiae Et Therapiae Experimentalis·Maciej SzymczakMarian Klinger

Related Concepts

Electrophoresis, Agar Gel
Enzymes, antithrombotic
SDS-PAGE
Gamma-glutamyl transferase
Alkaline Phosphatase Measurement
Cholestasis, Extrahepatic
Gamma Glutamyl Transferase Measurement
Alkaline Phosphatase
Phosphoglycerate Dehydrogenase Activity
Gel Chromatography

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Synapse Loss as Therapeutic Target in MS

As we age, the number of synapses present in the human brain starts to decline, but in neurodegenerative diseases this occurs at an accelerated rate. In MS, it has been shown that there is a reduction in synaptic density, which presents a potential target for treatment. Here is the latest research on synapse loss as a therapeutic target in MS.

Artificial Intelligence in Cardiac Imaging

Artificial intelligence (ai) techniques are increasingly applied to cardiovascular (cv) medicine in cardiac imaging analysis. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

Social Learning

Social learning involves learning new behaviors through observation, imitation and modeling. Follow this feed to stay up to date on the latest research.

Cell Atlas of the Human Eye

Constructing a cell atlas of the human eye will require transcriptomic and histologic analysis over the lifespan. This understanding will aid in the study of development and disease. Find the latest research pertaining to the Cell Atlas of the Human Eye here.

Single Cell Chromatin Profiling

Techniques like ATAC-seq and CUT&Tag have the potential to allow single cell profiling of chromatin accessibility, histones, and TFs. This will provide novel insight into cellular heterogeneity and cell states. Discover the latest research on single cell chromatin profiling here.

Genetic Screens in iPSC-derived Brain Cells

Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells.