Serum gastrin values in patients with familial adenomatous polyposis

Diseases of the Colon and Rectum
L B SvendsenF Stadil


An evaluation of the importance of gastrin in the colorectal carcinogenesis in patients with familial adenomatous polyposis was conducted. Blood samples from 168 family members of 26 families were investigated for circulating gastrin. Blood was drawn from 65 affected patients, 66 clinically unaffected first-degree relatives, and 37 spouses. We did not find any difference in distribution of serum gastrin among these groups. Our results seem to exclude gastrin from being relevant in early carcinogenesis in patients with familial adenomatous polyposis.


Jan 1, 1978·Scandinavian Journal of Gastroenterology·K C ChristensenJ F Rehfeld
Jan 1, 1990·Journal of Cancer Research and Clinical Oncology·E Tahara
Jun 1, 1990·Cell·E R Fearon, B Vogelstein
Apr 14, 1989·Science·B VogelsteinR White
Apr 1, 1989·British Journal of Cancer·S A WatsonD Morris
Sep 1, 1988·The New England Journal of Medicine·B VogelsteinJ L Bos
Feb 1, 1989·Digestive Diseases and Sciences·J P SmithT E Solomon
Sep 1, 1988·Diseases of the Colon and Rectum·H SuzukiH Terashima
Mar 1, 1988·American Journal of Surgery·C M TownsendJ C Thompson
Jun 1, 1988·Annals of Surgery·J R UppJ C Thompson
Aug 1, 1988·Journal of Surgical Oncology·H B KooJ J Decosse
Oct 1, 1986·The American Journal of Physiology·J M Mullin, T G O'Brien
Oct 1, 1985·Cancer Letters·D A KarlinM M Romsdahl
Oct 1, 1972·Scandinavian Journal of Clinical and Laboratory Investigation·J F RehfeldB Rubin
Dec 1, 1972·Scandinavian Journal of Clinical and Laboratory Investigation·F Stadil, J F Rehfeld
Jun 1, 1973·Scandinavian Journal of Clinical and Laboratory Investigation·J F Rehfeld, F Stadil
Jul 12, 1984·The New England Journal of Medicine·G D Luk, S B Baylin
Nov 1, 1982·The American Journal of Physiology·A E Pegg, P P McCann


May 1, 1999·Diseases of the Colon and Rectum·Amosy E M'KomaL Liljeqvist
Nov 18, 2003·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·C C ChungM K W Li
Apr 10, 2014·Journal of Gastroenterology and Hepatology·Adrienne C PatersonArthur Shulkes
Jun 20, 2007·International Journal of Colorectal Disease·Amosy E M'KomaAlan J Herline
Apr 22, 2020·Proceedings·Kyle M Rowe, Lawrence R Schiller

Related Concepts

Age Factors
Anastomosis, Surgical
Familial Intestinal Polyposis
Viral Markers
Proctocolectomy, Restorative

Related Feeds

Adenomatous Polyposis Coli

Adenomatous polyposis coli is a protein encoded by the APC gene and acts as a tumor suppressor. Discover the latest research on adenomatous polyposis coli here.