PMID: 18038711Nov 28, 2007

Serum ghrelin concentration, fasting time and feeding in infants

Journal of Pediatric Endocrinology & Metabolism : JPEM
F SavinoR Miniero


Data on hormonal feeding control in infants in the first months of life according to the kind of feeding are scanty. To evaluate whether serum ghrelin could be involved in feeding behaviour control of breast-fed (BF) and formula fed (FF) infants. We studied 50 AGA healthy term infants aged 1-6 months of age. Serum ghrelin concentration was determined by RIA. Fasting time (measured as the difference between the time of the last meal and the time of blood collection) and number of meals were recorded. A positive correlation between serum ghrelin levels and fasting time emerged in FF infants (r = 0.752; p <0.001) but not in BF infants (r = 0.345; p = 0.072). Circulating ghrelin concentration correlates positively with fasting time in FF infants; these infants have higher serum ghrelin concentration, longer fasting time and fewer meals than BF infants. These observations suggest a possible influence of early feeding on mechanisms regulating satiety and feeding behaviour.


Jan 24, 1998·The American Journal of Clinical Nutrition·Kathryn Dewey
Apr 21, 2001·Gastroenterology·J A Pilla, S D Zucker
Dec 5, 2002·Annals of Nutrition & Metabolism·Erika SieversJürgen Schaub
Dec 6, 2002·The Journal of Clinical Endocrinology and Metabolism·Germán IñiguezVeronica Mericq
Apr 8, 2003·The Journal of Clinical Endocrinology and Metabolism·David S WeigleJonathan Q Purnell
Aug 9, 2003·Journal of Endocrinological Investigation·D O'ConnorK Leef
Nov 7, 2003·The Journal of Clinical Endocrinology and Metabolism·Palmiero MonteleoneMario Maj
Apr 9, 2004·The Journal of Clinical Endocrinology and Metabolism·Tracey McLaughlinDavid E Cummings
Jun 9, 2004·Frontiers in Neuroendocrinology·Márta KorbonitsAshley B Grossman
Nov 3, 2004·The Journal of Pediatrics·Michael S KramerPromotion of Breastfeeding Intervention Trials Study Group
Sep 30, 2005·Peptides·Suleyman AydinSelahattin Kumru
Oct 29, 2005·Journal of Pediatric Gastroenterology and Nutrition·Anthony F Philipps
Oct 29, 2005·Journal of Pediatric Gastroenterology and Nutrition·F SavinoR Miniero
Mar 9, 2006·The Journal of Clinical Endocrinology and Metabolism·S BelloneG Bona
Mar 25, 2006·Endocrinology·Katrin AckermannJörg H Stehle
Apr 14, 2006·Journal of Pharmacological Sciences·Hiroshi HosodaKenji Kangawa
May 3, 2006·Clinical Endocrinology·F SavinoR Oggero
May 11, 2006·The American Journal of Clinical Nutrition·Lisa J MartinArdythe L Morrow
Jul 25, 2006·Physiology & Behavior·David E Cummings
Aug 3, 2006·Acta Paediatrica·Jennifer A KiersonMichael L Spear


Jul 16, 2011·International Journal of Pediatrics·F SavinoR Oggero
Apr 30, 2011·World Journal of Gastroenterology : WJG·F SavinoR Oggero
Jan 31, 2012·Early Human Development·F SavinoL Silvestro
Oct 24, 2007·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·F Savino, S A Liguori
Feb 15, 2013·Obesity·Jessica SchuelerD Enette Larson-Meyer

Related Concepts

Breast Feeding, Exclusive
Feeding Patterns
Infant Food
GHRL Protein

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Synthetic Genetic Array Analysis

Synthetic genetic arrays allow the systematic examination of genetic interactions. Here is the latest research focusing on synthetic genetic arrays and their analyses.

Neural Activity: Imaging

Imaging of neural activity in vivo has developed rapidly recently with the advancement of fluorescence microscopy, including new applications using miniaturized microscopes (miniscopes). This feed follows the progress in this growing field.

Computational Methods for Protein Structures

Computational methods employing machine learning algorithms are powerful tools that can be used to predict the effect of mutations on protein structure. This is important in neurodegenerative disorders, where some mutations can cause the formation of toxic protein aggregations. This feed follows the latests insights into the relationships between mutation and protein structure leading to better understanding of disease.

Congenital Hyperinsulinism

Congenital hyperinsulinism is caused by genetic mutations resulting in excess insulin secretion from beta cells of the pancreas. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Epigenetic Memory

Epigenetic memory refers to the heritable genetic changes that are not explained by the DNA sequence. Find the latest research on epigenetic memory here.

Cell Atlas of the Human Eye

Constructing a cell atlas of the human eye will require transcriptomic and histologic analysis over the lifespan. This understanding will aid in the study of development and disease. Find the latest research pertaining to the Cell Atlas of the Human Eye here.

Femoral Neoplasms

Femoral Neoplasms are bone tumors that arise in the femur. Discover the latest research on femoral neoplasms here.