PMID: 16633118Apr 25, 2006Paper

Serum ghrelin levels in children with celiac disease

Journal of Clinical Gastroenterology
Mukadder Ayse SelimogluFatih Akcay

Abstract

Ghrelin, a gastrointestinal hormone, has effects on nutrient intake and growth. Because celiac disease (CD) has intestinal histopathologic alterations and subsequent malnutrition and/or growth failure, we hypothesized that there would be alterations in serum ghrelin levels of those patients. In this study, we aimed to determine serum ghrelin levels in childhood CD, to observe probable alterations under gluten-free diet (GFD), and to see whether there is a relationship between ghrelin levels and the presentation of the disease and/or diet compliance. Thirty-six children with CD and 10 healthy children were included. Serum fasting ghrelin level was measured using radioimmunoassay method. After 6 months under GFD, sera of 19 patients were retested for ghrelin level. Mean serum ghrelin levels in children with CD and in controls were 478.2+/-154.6 and 108.3+/-49.1 pg/mL, respectively (P<0.001). Serum ghrelin level was not different in different clinical presentations. Ghrelin was negatively correlated with body mass index, both in healthy children and in children with CD on admission (P<0.01). Ghrelin level was lower after 6 months under GFDcompared with the level detected on admission (P<0.001), but was still higher compared with t...Continue Reading

References

Oct 19, 1999·European Journal of Gastroenterology & Hepatology·G OberhuberH Vogelsang
Nov 1, 2000·Nature·M TschöpM L Heiman
Nov 27, 2001·European Journal of Endocrinology·B Stoffel-Wagner
Jul 11, 2002·Endocrine Research·Michal KrsekZuzana Jarkovská
Apr 8, 2003·The Journal of Clinical Endocrinology and Metabolism·Jara NedvídkováKarel Pacak
Nov 18, 2003·Clinical Endocrinology·A J WhatmoreP E Clayton
Nov 26, 2003·The American Journal of Gastroenterology·Maddalena PeracchiMaria Teresa Bardella
Dec 3, 2003·Eating and Weight Disorders : EWD·M KrsekZ Jarkovská
Mar 9, 2004·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Akio InuiMineko Fujimiya
Apr 9, 2004·The Journal of Clinical Endocrinology and Metabolism·Simonetta BelloneGianni Bona
Jul 2, 2004·Anales de pediatría : publicación oficial de la Asociación Española de Pediatría (A.E.P.)·L Soriano-GuillénJ Argente
Jul 27, 2004·Current Opinion in Pediatrics·Carlo Catassi, Alessio Fasano
Aug 6, 2005·Journal of Clinical Gastroenterology·Vildan ErtekinEsin Aktaş

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Citations

Jan 20, 2012·The American Journal of Clinical Nutrition·Isabel CominoCarolina Sousa
Oct 2, 2009·Journal of Endocrinological Investigation·E Jarocka-CyrtaM Kaczmarski
Apr 15, 2014·Archivum Immunologiae Et Therapiae Experimentalis·Flavia Prodam, Nicoletta Filigheddu
Oct 29, 2008·Journal of Pediatric Gastroenterology and Nutrition·Kevin A HommelWallace V Crandall
Apr 5, 2011·Molecular and Cellular Endocrinology·Penny JefferyMichael McGuckin
Oct 22, 2008·Pediatrics International : Official Journal of the Japan Pediatric Society·Sevin AltinkaynakBuket Kilicarslan
May 3, 2008·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·A RoccoG Nardone
Oct 25, 2013·European Journal of Clinical Investigation·Maria PapastamatakiChristina Kanaka-Gantenbein
Mar 26, 2014·Autoimmune Diseases·Antonio CalabròLeonardo Tenori
Jun 11, 2008·Current Opinion in Clinical Nutrition and Metabolic Care·Mayra M Kamiji, Akio Inui
Sep 1, 2014·Expert Review of Endocrinology & Metabolism·Cristina MeazzaMauro Bozzola

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