PMID: 44628Oct 1, 1979

Serum IgG, IgA and IgM changes during infectious complications induced by facultative pathogenic gram-negative bacteria

Zentralblatt Für Bakteriologie, Parasitenkunde, Infektionskrankheiten Und Hygiene. Erste Abteilung Originale. Reihe A: Medizinische Mikrobiologie Und Parasitologie
G Petrás, K Merétey


IgG, IgA, and IgM concentrations were measured at 40 acute and 9 chronic patients continuously during complications induced by facultative pathogenic Gram-negative bacteria, primarily by Pseudomonas aeruginosa. On the basis of the results the sudden decrease of Ig concentrations at the onset of complications, during shock, and before death was, beside the consuming effect of antigen-antibody reactions, most probably a consequence of increased capillary permeability and haemodinamic disorders due to antigen-antibody reactions and the effect of endotoxin. It was conspicuous, that a correlation could be found between the concentration of IgM and the development or final outcome of the complications: IgM values in cases of lethal complications in the acute patients were essentially lower than in the other patients surviving severe complications, even at the early period of complications still without any clinical signs of the outcome.

Related Concepts

Pseudomonas Infections
Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Endotoxic Shock
Pseudomonas aeruginosa
Immunodiffusion Measurement
Bacterial Infections

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Sexual Dimorphism in Neurodegeneration

There exist sex differences in neurodevelopmental and neurodegenerative disorders. For instance, multiple sclerosis is more common in women, whereas Parkinson’s disease is more common in men. Here is the latest research on sexual dimorphism in neurodegeneration

HLA Genetic Variation

HLA genetic variation has been found to confer risk for a wide variety of diseases. Identifying these associations and understanding their molecular mechanisms is ongoing and holds promise for the development of therapeutics. Find the latest research on HLA genetic variation here.

Super-resolution Microscopy

Super-resolution microscopy is the term commonly given to fluorescence microscopy techniques with resolutions that are not limited by the diffraction of light. Here are the latest discoveries pertaining to super-resolution microscopy.

Genetic Screens in iPSC-derived Brain Cells

Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells.

Brain Lower Grade Glioma

Low grade gliomas in the brain form from oligodendrocytes and astrocytes and are the slowest-growing glioma in adults. Discover the latest research on these brain tumors here.

CD4/CD8 Signaling

Cluster of differentiation 4 and 8 (CD8 and CD8) are glycoproteins founds on the surface of immune cells. Here is the latest research on their role in cell signaling pathways.

Alignment-free Sequence Analysis Tools

Alignment-free sequence analyses have been applied to problems ranging from whole-genome phylogeny to the classification of protein families, identification of horizontally transferred genes, and detection of recombined sequences. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Related Papers

Acta Microbiologica Academiae Scientiarum Hungaricae
G Petrás, C Németh
Journal of Trace Elements in Medicine and Biology : Organ of the Society for Minerals and Trace Elements (GMS)
Sema BozalioğluBolkan Simşek
© 2020 Meta ULC. All rights reserved