Sep 1, 1977

Serum immunoglobulin levels in the course of anaphylactoid purpura in children

Acta paediatrica Scandinavica
S SimiläM Lanning


Serum levels of immunoglobulins (IgG, IgA, IgM, IgD and IgE) were determined at frequent intervals in the course of anaphylactoid purpura (AP) in children. AP was cured without complications in 16 out of 26 cases, recurring in 7 cases. Melena was manifested in 9 cases and nephropathy in 5. The levels of IgA and IgM were elevated in AP, but serum IgG, IgD and IgE showed no significant changes. The serum level of IgM was significantly (p less than 0.0125) higher in patients with AP nephropathy than in those with recent AP. The elevated serum IgA and IgM levels are possibly related to the pathogenesis of AP and/or its renal involvement.

Mentioned in this Paper

Pathogenic Aspects
Feces Color: Tarry
Serum Immunoglobulin A
Purpura Hemorrhagica
Melena due to Gastrointestinal Hemorrhage
Henoch-Schoenlein Purpura

About this Paper

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