Serum immunoglobulins in healthy children and adults. Levels of the five classes, expressed in international units per millilitre

Clinica Chimica Acta; International Journal of Clinical Chemistry
B ZegersR E Ballieux

Abstract

Serum levels of IgM, IgG, IgA, IgD, and IgE were determined in serum samples of 270 healthy Dutch children (aged 4-13 years) and of 30 healthy Dutch adults, the amounts being expressed in International Units per millilitre. Special attention is given to the IgD and IgE results, since the IgM, IgG, and IgA levels in mg per 100 ml of these sera and their implications have already been reported. In the children's sera the occurrence of relatively high IgD and IgE levels was frequently observed, whereas the adult group did not show excessive variation in this respect. The mean IgD levels found for adult males and females are 21 I.U./ml and 24 I.U./ml, respectively; the mean IgE levels for the same groups are 68 I.U./ml and 88 I.U./ml, respectively. The mean IgD and IgE levels in the children of each year group were usually higher than those of each of the juvenile groups and the mean level of the adult group was not statistically significant. A statistically significant influence of sex and season on the IgD and IgE levels could not be demonstrated in this material either. Three of the 270 children's sera showed an exceptionally low IgA content. In two of these cases the serum was sampled and studied a second time after an interval...Continue Reading

References

Nov 19, 1970·The New England Journal of Medicine·E B RosenbergS G Johansson
Jun 3, 1972·Lancet·B C ShanleyJ D North-Coombes
Jun 17, 1967·Nature·M ButterworthM Allansmith
Aug 28, 1969·The New England Journal of Medicine·A J AmmannR A Good
Sep 1, 1969·Acta paediatrica Scandinavica·T Berg, S G Johansson
Jan 1, 1973·International Archives of Allergy and Applied Immunology·E E Reerink-BrongersP C Sander
May 1, 1973·Immunochemistry·R C AalberseE E Reerink-Brongers
Oct 1, 1973·The Journal of Experimental Medicine·D S RoweB Pernis
Sep 1, 1965·Immunochemistry·G ManciniJ F Heremans
Mar 11, 1971·The New England Journal of Medicine·D P Schwartz, R H Buckley
Mar 11, 1971·The New England Journal of Medicine·R A Good, Y S Choi
Jan 1, 1965·Scandinavian Journal of Clinical and Laboratory Investigation·R Bachmann
Jan 1, 1965·The Journal of Experimental Medicine·D S ROWE, J L FAHEY
Apr 30, 2008·The Journal of Cell Biology·David MichaelsonMark R Philips

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Citations

Sep 1, 1989·Journal of Clinical Immunology·I HiemstraB J Zegers
Jan 1, 1993·The Journal of Allergy and Clinical Immunology·L A SandersB J Zegers
Apr 3, 2001·Molecular Immunology·J L Preud'hommeE Lelièvre
Mar 29, 2000·Scandinavian Journal of Immunology·A HaraldssonI Klasen
Sep 1, 1991·Clinical and Experimental Dermatology·I M BergbrantT Söderström
Nov 1, 1979·International Journal of Dermatology·G F HendrickxJ W Stoop
May 1, 1973·Vox Sanguinis·B J ZegersP C Sander
Aug 1, 1978·The Journal of Clinical Investigation·S L DunnetteR M Weinshilboum
Dec 1, 1983·The Journal of Clinical Investigation·E van LoghemL Kater
Oct 4, 2014·Emerging Infectious Diseases·Anita K McElroyChristina F Spiropoulou
Feb 1, 1979·American Journal of Physical Anthropology·H W GoeddeE Kleihauer
Sep 5, 2012·Molecular Immunology·Nien-Yi ChenTse-Wen Chang
Jun 23, 2012·PLoS Neglected Tropical Diseases·Nádia C DüppreSamira Bührer-Sékula
Dec 7, 2013·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Vincent R Bonagura
Nov 12, 2015·Glycoconjugate Journal·Florent ClercManfred Wuhrer
Sep 5, 2020·Journal of Neuroinflammation·Sven JariusUNKNOWN in cooperation with the BIOMARKER study group and the Neuromyelitis optica Study Group (NEMOS)
Jan 8, 2021·International Reviews of Immunology·Tue Gia Nguyen
Feb 27, 2021·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Javad GhorbaniElham Tahmasebi
Apr 27, 2021·Frontiers in Immunology·Samer R KhanLayal Chaker

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