PMID: 2494289Mar 1, 1989Paper

Serum inhibin levels in normal men and men with testicular disorders

The Journal of Endocrinology
D M de KretserH G Burger

Abstract

Serum concentrations of inhibin, FSH and LH were measured in 39 normal men and 127 men with testicular disorders resulting in infertility. The infertile men were divided into groups on the basis of their mean sperm count, FSH levels and karyotype. The mean (+/- S.D) serum concentrations of inhibin in the normal men was 554 +/- 156 U/l and did not differ significantly from those groups with oligospermia, azoospermia or Klinefelter's syndrome. Combined analyses of all groups did not reveal any significant correlation between serum concentrations of inhibin and FSH or with any other parameter measured. Serum concentrations of FSH and LH were positively correlated, and Leydig cell dysfunction, as evidenced by increased serum LH levels, low testosterone levels or a declining testosterone/LH ratio were found with severe spermatogenic damage. The failure of serum concentrations of inhibin to correlate with those of FSH levels or the degree of testicular damage raise questions as to the clinical value of this parameter alone.

Citations

Jan 1, 1992·Journal of Clinical Ultrasound : JCU·T H ShawkerL K Nieman
Sep 1, 1989·Molecular and Cellular Endocrinology·G P RisbridgerD M de Kretser
Aug 6, 2000·Fertility and Sterility·B A KolbR Z Sokol
Jul 14, 2001·Molecular and Cellular Endocrinology·R A Anderson
Apr 25, 2000·Molecular and Cellular Endocrinology·D M de KretserK A Loveland
Mar 8, 2000·Experimental Gerontology·H G Burger
Apr 1, 1992·Baillière's Clinical Endocrinology and Metabolism·D M RobertsonD M de Kretser
Apr 1, 1992·Baillière's Clinical Endocrinology and Metabolism·C Wang, R S Swerdloff
Jun 9, 2000·International Journal of Andrology·R A Anderson, R M Sharpe
Nov 26, 1998·Journal of Pediatric Endocrinology & Metabolism : JPEM·C A LonguiW Bloise
Dec 1, 1992·Annals of Medicine·H G Burger
Jan 1, 1989·Annals of the New York Academy of Sciences·H G BurgerD M De Kretser
Sep 26, 2006·European Urology·Stephen J BromageStephen R Payne
Feb 13, 2003·Clinical Endocrinology·Stephen TongHenry G Burger
Jan 1, 1994·Clinical Endocrinology·M BergmannE Nieschlag
Feb 1, 1993·Clinical Endocrinology·E Nieschlag
Apr 1, 1990·Clinical Endocrinology·B C FauserF H De Jong
Oct 1, 1996·British Journal of Obstetrics and Gynaecology·E M Wallace, D L Healy
Apr 1, 1997·Endocrinology·H G Burger, D M Robertson
Nov 7, 2001·Archives of Andrology·M FujisawaS Kamidono
Dec 12, 2001·Endocrine Reviews·G P RisbridgerD M Robertson
Jun 17, 1998·The Journal of Clinical Endocrinology and Metabolism·F J HayesW F Crowley
Jan 30, 2003·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·S YaltiC Fiçicioglu
Jul 1, 1990·Journal of Endocrinological Investigation·D M de KretserG P Risbridger
Jun 12, 2018·Systems Biology in Reproductive Medicine·Grigory A Demyashkin
Nov 7, 1998·Archives of Andrology·I SasagawaH Miura

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