PMID: 20954115Oct 19, 2010

Serum levels of macrophage migration inhibitory factor and leptin in patients with acute trichinellosis

Türkiye parazitolojii dergisi
Leyla Didem KozaciFatoş Onen

Abstract

The aim of this study was to examine the serum levels of MIF and leptin in patients infected with Trichinella britovi. Thirtysix patients with acute trichinellosis and 20 healthy control subjects were included in the study. Serum high sensitive C-reactive protein (hs-CRP), MIF and leptin levels were studied. Assessments were performed in the patients group during acute infection and after the treatment periods and we also compared these values with healthy controls. In the patients, hs-CRP, leukocyte and eosinophil counts, and the levels of muscle enzymes in the acute infectious period were found to be significantly higher than those in the post treatment period (p < 0.05). Both leptin and MIF were higher in acute trichinellosis patients when compared to controls. However, this was only significant for leptin. This study indicates that leptin and MIF levels are increased in the sera of patients with acute trichinellosis.

Related Concepts

Acute Disease
SGOT - Glutamate oxaloacetate transaminase
C-reactive protein
Macro-Creatine Kinase
Disease Outbreaks
Eosinophil
Lactate Dehydrogenase
Differential White Blood Cell Count Procedure
Migration Inhibition Factor, Macrophage
Plasma Albumin

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