Serum levels of natriuretic peptides in patients with Behcet's disease.

Clinical Rheumatology
Ramazan YağciMeral Ekşioğlu

Abstract

The objective of our study was to elucidate serum levels of atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), and C-type natriuretic peptide (CNP) in Behcet's disease (BD) patients with active and inactive period. The multicenter study included 53 patients with active (n = 28) and inactive (n = 25) BD (mean age, 34.3 +/- 9 years; 15 men and 38 women) satisfying the International Study Group criteria and 26 healthy controls (mean age, 34.4 +/- 6.1 years; seven men and 19 women) matched for age and gender from a similar ethnic background. Serum natriuretic peptides levels were determined by enzyme immunoassay kit. Mean serum ANP concentrations in the active patients (4.01 +/- 1.21 ng/ml) were significantly lower than in the healthy controls (5.76 +/- 1.99 ng/ml, p = 0.004). Mean serum BNP levels were found to be significantly higher in both the active (6.19 +/- 2.97 ng/ml) and inactive (6.49 +/- 2.88 ng/ml) BD groups compared with the control group (3.82 +/- 1.1 ng/ml, p = 0.004 and p = 0.001, respectively). Mean serum CNP concentrations in the active patients (0.49 +/- 0.12 ng/ml) were significantly lower than in the inactive patients (0.65 +/- 0.2 ng/ml, p = 0.017) and the healthy controls (0.8 +/- 0.27 ng/ml, ...Continue Reading

References

Jan 1, 1992·Annual Review of Physiology·T Maack
Jun 24, 1992·Journal of Immunological Methods·S Avrameas
Jun 24, 1992·Journal of Immunological Methods·T Porstmann, S T Kiessig
Jun 5, 1998·The Journal of Biological Chemistry·A K Kiemer, A M Vollmar
Feb 23, 1999·Dermatology : International Journal for Clinical and Investigative Dermatology·A OremM Malkoç
Oct 21, 1999·The New England Journal of Medicine·T SakaneG Inaba
Dec 10, 1999·Rheumatology·C G Barnes, H Yazici
Jan 9, 2001·Dermatology : International Journal for Clinical and Investigative Dermatology·C EverekliogluH S Inaloz
Jan 10, 2001·Current Opinion in Rheumatology·H YaziciV Hamuryudan
Feb 17, 2001·American Journal of Physiology. Heart and Circulatory Physiology·M B HussainA J Hobbs
Aug 2, 2003·Rheumatology·G LawtonA Tennant
Feb 13, 2004·The New England Journal of Medicine·Thomas J WangRamachandran S Vasan
Feb 14, 2004·Basic Research in Cardiology·Amrita AhluwaliaAdrian J Hobbs
Jun 19, 2004·The International Journal of Biochemistry & Cell Biology·S D ChauhanA Ahluwalia
Jul 24, 2004·The British Journal of Dermatology·C YaziciF Ateş
Jan 27, 2005·Pharmacology & Therapeutics·Ramona S ScotlandAdrian J Hobbs
Mar 9, 2005·Journal of the European Academy of Dermatology and Venereology : JEADV·S BekpinarZ Ozbek-Kir
May 25, 2005·Peptides·Angelika M Vollmar
Aug 12, 2005·Mayo Clinic Proceedings·Paul M McKie, John C Burnett
Aug 16, 2005·Respiratory Medicine·David G KielyBrian J Lipworth
Oct 7, 2005·Arthritis Research & Therapy·Yu LuEdward K L Chan
Jan 13, 2006·Journal of Thrombosis and Haemostasis : JTH·M SöhneH R Büller
May 23, 2006·Rheumatology International·Aylin Sepici-DinçelBolkan Simşek
Jan 9, 2007·Clinical Rheumatology·Seyithan TaysiRefik Ali Sari
Jan 25, 2007·Clinical Chemistry and Laboratory Medicine : CCLM·Yeşim OzkanBolkan Simşek
Feb 14, 2007·Archives of Ophthalmology·Kumiko NakaoTaiji Sakamoto
Jun 6, 2007·The Tohoku Journal of Experimental Medicine·Ahmet IsikSahabettin Selek

❮ Previous
Next ❯

Citations

Dec 17, 2008·Current Opinion in Rheumatology·Garvan C Kane, Karina A Keogh
Oct 7, 2011·Pathology Research International·Umit Türsen
Apr 4, 2013·Journal of Negative Results in Biomedicine·Andreas KuehnlHans-Henning Eckstein
Jun 2, 2016·International Journal of Rheumatology·Fawad AslamMahboob Alam
Jun 17, 2011·European Journal of Echocardiography : the Journal of the Working Group on Echocardiography of the European Society of Cardiology·Julide YagmurRamazan Ozdemir
Mar 1, 2019·Reproduction : the Official Journal of the Society for the Study of Fertility·Guangyin XiJianhui Tian

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.