Serum levels of testosterone precursors, testosterone and estradiol in 10 animal species

Experimental and Clinical Endocrinology
U WichmannW Krause

Abstract

Blood levels of testosterone precursors, i.e. pregnenolone, progesterone, 17 alpha-hydroxyprogesterone, androstendione, DHEA, and delta 5-androstendiol as well as testosterone and estradiol are measured in 10 animals each of 10 different species. The determination is done by radioimmunoassay with steroidspecific antibodies. Precursors of the delta 5-pathway (DHEA, androstendiol) are low in the red deer, dog, cat, rat and guinea pig. Precursors of the delta 4-pathway (progesterone, 17-hydroxprogesterone, androstendione) are lower in the bull, boar, ram, stallion and rabbit thus indicating a predominance of different pathways in the animal species studied herein. Pregnenolone concentrations are of equal height in all animals, testosterone is lowest in the cat and stallion. In the latter species the estradiol/testosterone ratio is spectacular high.

Citations

Nov 1, 1994·Comparative Biochemistry and Physiology. Part C, Pharmacology, Toxicology & Endocrinology·T FehérE Sándor
Aug 15, 2009·Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment·J ScarthJ Kay
Aug 3, 2001·General and Comparative Endocrinology·K K Soma, J C Wingfield
Feb 20, 2004·Archives of Physiology and Biochemistry·G GenaroA A M Rosa e Silva
Nov 11, 2005·Steroids·Noriko TagawaYoshiharu Kobayashi
Oct 9, 2004·The Journal of Veterinary Medical Science·Toshihiko TsutsuiTatsuya Hori
Jul 11, 2014·The Journal of Steroid Biochemistry and Molecular Biology·Nancy H IngThomas H Welsh
Aug 30, 2000·Proceedings of the Society for Experimental Biology and Medicine·D R Pieper, C A Lobocki
Sep 1, 1988·Journal of Endocrinological Investigation·M G KentS S Wachtel
Oct 12, 2002·American Journal of Physiology. Endocrinology and Metabolism·Mark A YorekJoseph S Dillon
Jan 15, 2021·Differentiation; Research in Biological Diversity·Rex A HessBarry T Hinton
Jul 1, 1987·Metabolism: Clinical and Experimental·C LongcopeL E Braverman

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