Serum lipase for assessment of pancreatic trauma

European Journal of Trauma and Emergency Surgery : Official Publication of the European Trauma Society
Biswadev MitraC Atkin

Abstract

Pancreatic enzymes are routinely measured during reception of trauma patients to assess for pancreatic injury despite conflicting evidence on their utility. The aim of this study was to investigate the utility of routine initial serum lipase measurement for the diagnosis of acute pancreatic trauma. Lipase measurements were introduced as part of the trauma pathology panel and requested on all patients who presented to an adult major trauma service and met trauma call-out criteria. Clinical records of these patients were extracted from the trauma registry and retrospectively reviewed. The performance of an initial serum lipase level measured on presentation to detect pancreatic trauma was determined. There were 2,580 patients included in the study, with 17 patients diagnosed with pancreatic trauma. An elevated lipase was recorded in 390 patients. Statistically significant associations were observed for elevated lipase in patients with pancreatic trauma, head injury, acute alcohol ingestion and massive blood transfusion. As a test for pancreatic trauma, an abnormal serum lipase result had a specificity of 85.3 % (95 % CI 83.8-86.6), sensitivity of 76.5 % (95 % CI 49.8-92.2), positive predictive value of 3.3 % (95 % CI 1.8-5.8) and...Continue Reading

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Citations

Dec 24, 2019·World Journal of Emergency Surgery : WJES·Federico CoccoliniUNKNOWN WSES-AAST Expert Panel
Feb 23, 2021·The Journal of Trauma and Acute Care Surgery·Emilie JoosUNKNOWN Canadian Collaborative on Urgent Care Surgery (CANUCS)

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