Serum lipid levels and 3-month prognosis in Chinese patients with acute stroke

Advances in Therapy
Wei LiSong Tan

Abstract

The possible correlation between serum lipid levels and outcome after stroke is still controversial. Therefore we examined whether serum lipid levels at admission had any prognostic value in the 3-month outcome after stroke. We performed a prospective, observational study of 649 patients with acute ischaemic stroke and intracerebral haemorrhagic stroke (ICH). Information on age, sex, history of arterial hypertension, diabetes mellitus, drinking, current smoking status, stroke type, Glasgow Coma Scale and Scandinavian Stroke Scale score, time from stroke onset, and presence of atrial fibrillation was obtained. Serum lipid levels were measured in blood samples taken from fasting patients 12 to 48 hours following ictus. Death and poor neurological outcome (Modified Rankin Scale score of > or =3 points) were defined as outcome events. A logistic regression model was performed to estimate the effect of the above variables on outcome after stroke. We found that the median levels of serum total cholesterol (TC), triglycerides (TG) and high-density lipoprotein cholesterol (HDL-C) in good outcome patients with acute stroke were significantly higher (P<0.005) than those of poor outcome patients. The low levels of serum TC, TG and HDL-C (...Continue Reading

References

May 1, 1988·Stroke; a Journal of Cerebral Circulation·J C van SwietenJ van Gijn
Jul 13, 1974·Lancet·G Teasdale, B Jennett
May 31, 1997·BMJ : British Medical Journal·A G DykerK R Lees
May 24, 2000·Neurology·C VautheyJ Bogousslavsky
Sep 18, 2002·JAMA : the Journal of the American Medical Association·Sharon E StrausFinlay A McAlister
Dec 13, 2003·Stroke; a Journal of Cerebral Circulation·Carlos A MolinaUNKNOWN CLOTBUST Investigators
May 8, 2004·Stroke; a Journal of Cerebral Circulation·Tomasz DziedzicAndrzej Szczudlik

❮ Previous
Next ❯

Citations

Oct 5, 2012·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·P M RistT Kurth
Jun 1, 2010·Archives of Physical Medicine and Rehabilitation·Shin-Liang PanTony Hsiu-Hsi Chen
Apr 17, 2012·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Slaven PikijaDunja Dukši
Sep 22, 2016·International Journal of Stroke : Official Journal of the International Stroke Society·Samrat YeramaneniJane C Khoury
Jan 21, 2012·Cerebrovascular Diseases·Noriko MakiharaKazunori Toyoda
Jan 24, 2019·Lipids in Health and Disease·Tian-Li XiaDe-Jia Huang
Jan 1, 2013·Neuroscience Journal·Minal JainLatha Ganti Stead
Feb 18, 2020·Journal of Atherosclerosis and Thrombosis·Peiyang ZhouXifa Lan
Nov 20, 2016·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·Q-W DengF-L Yan
Aug 8, 2020·American Journal of Human Genetics·Allison MeisnerNilanjan Chatterjee

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atrial Filbrillation

Atrial fibrillation refers to the abnormal heart rhythm characterized by rapid and irregular beating of the atria. Here is the latest research.

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.

Brain Ischemia

Brain ischemia is a condition in which there is insufficient blood flow to the brain to meet metabolic demand. Discover the latest research on brain ischemia here.