PMID: 1193498Jan 1, 1975Paper

Serum lysozyme in mice subjected to combined immunosuppression with 6-mercaptopurine and hydrocortisone

Folia Microbiologica
J Prixová

Abstract

Simultaneous peroral administration of 6-mercaptopurine (80 mg/kg per day) and subcutaneous injection of hydrocortisone (1 mg/mouse per day) for ten days results in increased lethality and more pronounced decrease in total peripheral leukocyte count and serum lysozyme levels as compared with mice receiving each drug separately. The possible mechanism of this effect is discussed.

References

Jan 1, 1969·Journal of Bacteriology·R D PontefractF S Thatcher
Oct 1, 1969·Journal of Bacteriology·R J Sharbaugh, J B Grogan
Nov 1, 1966·The Journal of Experimental Medicine·E F Osserman, D P Lawlor
May 1, 1967·The Journal of Surgical Research·T S Harrison
Feb 1, 1969·The Journal of Pathology·J E Stevens, D A Willoughby
Oct 9, 1967·Biochimica Et Biophysica Acta·A NilssonH L Davids
Feb 1, 1968·Proceedings of the Society for Experimental Biology and Medicine·M E Fink, S C Finch

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