Serum magnesium and atherogenic lipid fractions in type II diabetic patients of Lahore, Pakistan

Biological Trace Element Research
Humaira RasheedHumayun Ajaz

Abstract

This study was conducted to determine the prevalence of hypomagnesemia and its effect on the lipid profile of local type II diabetic patients. For this purpose, 219 diabetic patients and 100 age-matched control subjects were enrolled. Blood samples of the subjects were analyzed for fasting glucose, Mg, triglyceride, total cholesterol, HDL-cholesterol, and LDL-cholesterol. Results showed that mean serum values of these parameters were differing in diabetic patients as compared to control subjects. The reference range of serum magnesium in healthy controls was 1.2-4.4 mg/dl. Mean serum magnesium in diabetic patients was significantly lower as compared to healthy subjects (1.6 ± 0.23 mg/dl vs. 2.8 ± 0.8 mg/dl). Among diabetic patients, 143 (65.3%) had serum magnesium level below 1.7 mg/dl (hypomagnesemia). The corresponding figure for control subjects was 11 (11%). The difference was significant (p < 0.01). Diabetes mellitus patients with current hyperglycemic status had significantly lower serum Mg as compared to euglycemic patients (p = 0.05). Serum Mg in diabetic patients was correlated with all lipid parameters. Among them, HDL-cholesterol was significantly (p < 0.05) positively correlated (r = 0.34), while total cholesterol a...Continue Reading

References

May 1, 1989·Atherosclerosis·P A MarkenM F Lopes-Virella
Jul 1, 1988·Annals of Emergency Medicine·S K GerardH Khayam-Bashi
Aug 1, 1995·Diabetic Medicine : a Journal of the British Diabetic Association·M S DjurhuusH Beck-Nielsen
Feb 12, 1998·The American Journal of Clinical Nutrition·A HaenniH Lithell
Mar 23, 2000·Clinica Chimica Acta; International Journal of Clinical Chemistry·N E SarisA Lewenstam
Sep 26, 2000·Scandinavian Journal of Clinical and Laboratory Investigation·M S DjurhuusN A Klitgaard
Dec 13, 2000·Journal of Diabetes and Its Complications·F Guerrero-Romero, M Rodríguez-Morán
Dec 6, 2001·Metabolism: Clinical and Experimental·M S DjurhuusJ E Henriksen
Oct 17, 2002·Endothelium : Journal of Endothelial Cell Research·David K JohnsonJames A Holland
May 28, 2004·Diabetes Research and Clinical Practice·Maryam Sadat FarvidNavid Saadat
Oct 7, 2004·Journal of the American College of Nutrition·Andrea Rosanoff, Mildred S Seelig
Oct 7, 2004·Journal of the American College of Nutrition·Kuninobu YokotaNaoko Tajima
Jul 1, 2006·Archives of Biochemistry and Biophysics·Mario Barbagallo, Ligia J Dominguez
Dec 13, 2006·Atherosclerosis·Edward W RandellGuang Sun
Jan 19, 2007·Journal of the American College of Nutrition·Earle C ChambersRichard N Pierson
Jan 17, 2008·Current Opinion in Lipidology·Simona Bo, Elisabetta Pisu

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Citations

May 24, 2018·The British Journal of Nutrition·Lianlong YuYing Jiang
Feb 6, 2017·Journal of Human Nutrition and Dietetics : the Official Journal of the British Dietetic Association·H Verma, R Garg
May 1, 2021·Nutrients·Mihnea-Alexandru GămanCamelia Cristina Diaconu

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