Serum salusin-β levels are associated with the presence and severity of coronary artery disease

Journal of Investigative Medicine : the Official Publication of the American Federation for Clinical Research
Jun LiuLi Kang

Abstract

We sought to assess whether serum salusin-β levels are correlated with the presence and severity of coronary artery disease (CAD). We measured serum salusin-β levels in 278 consecutive patients undergoing coronary angiography (CAG) for the evaluation of CAD and in 126 healthy controls. Serum salusin-β levels were measured by enzyme-linked immunosorbent assay. The severity of CAD was assessed by angiographic coronary atherosclerosis index score system. Serum salusin-β levels were significantly higher in patients undergoing CAG (n = 278) than those in healthy controls (n = 126) (3.81 ± 0.99 vs 4.34 ± 1.40 nmol/L, P < 0.01). In patients undergoing CAG, patients with CAD (n = 160) had significantly higher serum salusin-β levels compared to patients without CAD (n = 118) (4.65 ± 1.44 vs 3.94 ± 1.23 nmol/L, P < 0.01). Multivariate logistic regression analysis revealed that serum salusin-β levels were independently associated with the presence of CAD (odds ratio, 1.439; 95% confidence interval, 1.176-1.760; P < 0.01). Serum salusin-β levels were positively correlated with the coronary atherosclerosis index score (r = 0.316, P < 0.001). Serum salusin-β levels were associated with the presence and severity of CAD. Salusin-β in serum mig...Continue Reading

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Citations

May 27, 2016·Genetic Testing and Molecular Biomarkers·Tao WangHong-Yun Cao
Mar 16, 2017·Biotechnic & Histochemistry : Official Publication of the Biological Stain Commission·M CakirF Ozyalin
Sep 6, 2019·Cardiology in the Young·Pınar DervişoğluMehmet Köroğlu
Feb 12, 2017·Oncology Reports·Qian ZhangFang-Fang Zhu
Feb 15, 2020·The Journal of International Medical Research·Yuxue WangXiaolu Mao
Apr 20, 2021·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Sena Genç EldenHalil Elden

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